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TFCP2L1 transcription factor CP2 like 1 [ Homo sapiens (human) ]

Gene ID: 29842, updated on 1-Jun-2020

Summary

Official Symbol
TFCP2L1provided by HGNC
Official Full Name
transcription factor CP2 like 1provided by HGNC
Primary source
HGNC:HGNC:17925
See related
Ensembl:ENSG00000115112 MIM:609785
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LBP9; CRTR1; LBP-9
Expression
Biased expression in kidney (RPKM 25.1), salivary gland (RPKM 23.9) and 10 other tissues See more
Orthologs

Genomic context

See TFCP2L1 in Genome Data Viewer
Location:
2q14.2
Exon count:
17
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (121216587..121285210, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (121974163..122042778, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs522 Neighboring gene uncharacterized LOC105373588 Neighboring gene ribosomal protein S17 pseudogene 7 Neighboring gene cytoplasmic linker associated protein 1 Neighboring gene uncharacterized LOC107985942 Neighboring gene RNA, U4atac small nuclear (U12-dependent splicing)

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 
cytoplasm organization IEA
Inferred from Electronic Annotation
more info
 
determination of adult lifespan IEA
Inferred from Electronic Annotation
more info
 
epithelial cell maturation IEA
Inferred from Electronic Annotation
more info
 
female pregnancy TAS
Traceable Author Statement
more info
PubMed 
negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
positive regulation of growth IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
salivary gland development IEA
Inferred from Electronic Annotation
more info
 
steroid biosynthetic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transcription factor CP2-like protein 1
Names
CP2-related transcriptional repressor 1
CRTR-1
transcription factor LBP-9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014553.3NP_055368.1  transcription factor CP2-like protein 1

    See identical proteins and their annotated locations for NP_055368.1

    Status: VALIDATED

    Source sequence(s)
    AC013399, AC079988, BC064698, BM055156
    Consensus CDS
    CCDS2134.1
    UniProtKB/Swiss-Prot
    Q9NZI6
    Related
    ENSP00000263707.5, ENST00000263707.6
    Conserved Domains (2) summary
    cd09590
    Location:310376
    SAM_LBP9; SAM domain of LBP9 transcriptional factors
    pfam04516
    Location:34237
    CP2; CP2 transcription factor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    121216587..121285210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003902.1XP_016859391.1  transcription factor CP2-like protein 1 isoform X1

  2. XM_017003903.1XP_016859392.1  transcription factor CP2-like protein 1 isoform X2

  3. XM_017003905.1XP_016859394.1  transcription factor CP2-like protein 1 isoform X4

  4. XM_017003904.1XP_016859393.1  transcription factor CP2-like protein 1 isoform X3

    Conserved Domains (1) summary
    pfam04516
    Location:34237
    CP2; CP2 transcription factor
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