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SREK1IP1 SREK1 interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 285672, updated on 5-Aug-2022

Summary

Official Symbol
SREK1IP1provided by HGNC
Official Full Name
SREK1 interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:26716
See related
Ensembl:ENSG00000153006 AllianceGenome:HGNC:26716
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
P18SRP; SFRS12IP1
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in RNA splicing and mRNA processing. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in skin (RPKM 4.8), placenta (RPKM 4.5) and 25 other tissues See more
Orthologs
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Genomic context

See SREK1IP1 in Genome Data Viewer
Location:
5q12.3
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (64718148..64768691, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (65538272..65588810, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (64013975..64064518, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12830 Neighboring gene mitochondrial ribosomal protein L49 pseudogene 1 Neighboring gene shisa like 2B Neighboring gene uncharacterized LOC124900985 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:64063900-64065099 Neighboring gene CWC27 spliceosome associated cyclophilin Neighboring gene Sharpr-MPRA regulatory region 13369

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36754, MGC131910, MGC150548, MGC150549

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein SREK1IP1
Names
SFRS12-interacting protein 1
p18 splicing regulatory protein
protein SFRS12IP1
splicing regulatory protein of 18 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173829.4NP_776190.1  protein SREK1IP1

    See identical proteins and their annotated locations for NP_776190.1

    Status: VALIDATED

    Source sequence(s)
    AC008898, AK094073
    Consensus CDS
    CCDS34171.1
    UniProtKB/Swiss-Prot
    Q32NC8, Q8N9Q2
    Related
    ENSP00000427401.3, ENST00000513458.9
    Conserved Domains (1) summary
    pfam13917
    Location:930
    zf-CCHC_3; Zinc knuckle

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    64718148..64768691 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    65538272..65588810 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)