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Srek1ip1 splicing regulatory glutamine/lysine-rich protein 1interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 67288, updated on 5-Feb-2023

Summary

Official Symbol
Srek1ip1provided by MGI
Official Full Name
splicing regulatory glutamine/lysine-rich protein 1interacting protein 1provided by MGI
Primary source
MGI:MGI:1914538
See related
Ensembl:ENSMUSG00000021716 AllianceGenome:MGI:1914538
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sfrs12ip1; Srsf12ip1; 3110031B13Rik
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to act upstream of or within RNA splicing and mRNA processing. Is expressed in brain; central nervous system ganglion; and sensory organ. Orthologous to human SREK1IP1 (SREK1 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 7.1), CNS E11.5 (RPKM 6.5) and 28 other tissues See more
Orthologs
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Genomic context

See Srek1ip1 in Genome Data Viewer
Location:
13; 13 D1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (104953678..104975184)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (104817170..104838676)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 Neighboring gene predicted gene 8680 Neighboring gene predicted gene, 53810 Neighboring gene CWC27 spliceosome-associated protein Neighboring gene shisa like 2B Neighboring gene predicted gene, 41048 Neighboring gene H3 histone, family 3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
protein SREK1IP1
Names
SFRS12-interacting protein 1
SREK1-interacting protein 1
protein SFRS12IP1
serine/arginine-rich splicing factor 12, interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001409332.1NP_001396261.1  protein SREK1IP1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC137691
  2. NM_001409333.1NP_001396262.1  protein SREK1IP1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC137691
  3. NM_026075.4NP_080351.2  protein SREK1IP1 isoform 1

    See identical proteins and their annotated locations for NP_080351.2

    Status: VALIDATED

    Source sequence(s)
    AC137691
    Consensus CDS
    CCDS26753.1
    UniProtKB/Swiss-Prot
    Q4V9W2, Q9CXR0
    Related
    ENSMUSP00000022230.9, ENSMUST00000022230.15
    Conserved Domains (1) summary
    pfam13917
    Location:930
    zf-CCHC_3; Zinc knuckle

RNA

  1. NR_135272.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC137691
    Related
    ENSMUST00000156105.2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    104953678..104975184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)