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PLGLA plasminogen like A (pseudogene) [ Homo sapiens (human) ]

Gene ID: 285189, updated on 10-Oct-2023

Summary

Official Symbol
PLGLAprovided by HGNC
Official Full Name
plasminogen like A (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:9074
See related
Ensembl:ENSG00000291125 MIM:612212; AllianceGenome:HGNC:9074
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRGA; PLGP2; PLGLA1
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver (RPKM 55.0) and kidney (RPKM 2.5) See more
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Genomic context

See PLGLA in Genome Data Viewer
Location:
2q12.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (106382114..106391395)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (106842876..106852158)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (106998570..107007851)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16340 Neighboring gene ILRUN pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11848 Neighboring gene ANAPC1 pseudogene 6 Neighboring gene RANBP2 like and GRIP domain containing 3 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:107056244-107056460 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:107060799-107061300 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:107084140-107084332 Neighboring gene anaphase-promoting complex subunit 1-like Neighboring gene CD8B family member 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Other Names

  • plasminogen pseudogene 2
  • plasminogen-like A
  • plasminogen-like A1
  • plasminogen-related protein A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003506.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC114755, DA634686, U67178
    Related
    ENST00000484422.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    106382114..106391395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    106842876..106852158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)