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FAM126B family with sequence similarity 126 member B [ Homo sapiens (human) ]

Gene ID: 285172, updated on 18-Aug-2020

Summary

Official Symbol
FAM126Bprovided by HGNC
Official Full Name
family with sequence similarity 126 member Bprovided by HGNC
Primary source
HGNC:HGNC:28593
See related
Ensembl:ENSG00000155744
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HYCC2
Expression
Ubiquitous expression in brain (RPKM 5.2), fat (RPKM 4.3) and 25 other tissues See more
Orthologs

Genomic context

See FAM126B in Genome Data Viewer
Location:
2q33.1
Exon count:
19
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (200973718..201071671, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (201838441..201936392, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene NGG1 interacting factor 3 like 1 Neighboring gene RNA, U6 small nuclear 762, pseudogene Neighboring gene origin recognition complex subunit 2 Neighboring gene uncharacterized LOC105373835 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 35 Neighboring gene ribosomal protein L23a pseudogene 30 Neighboring gene RNA, U6 small nuclear 1206, pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit B3 Neighboring gene ribosomal protein L17 pseudogene 10

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10981, FLJ37917, FLJ42947, MGC39518

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
phosphatidylinositol phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein localization to plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IEA
Inferred from Electronic Annotation
more info
 
intracellular IDA
Inferred from Direct Assay
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321618.1NP_001308547.1  protein FAM126B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Consensus CDS
    CCDS2335.1
    UniProtKB/Swiss-Prot
    Q8IXS8
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  2. NM_001321619.2NP_001308548.1  protein FAM126B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Consensus CDS
    CCDS2335.1
    UniProtKB/Swiss-Prot
    Q8IXS8
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  3. NM_001321621.2NP_001308550.1  protein FAM126B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Consensus CDS
    CCDS2335.1
    UniProtKB/Swiss-Prot
    Q8IXS8
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  4. NM_001321622.2NP_001308551.1  protein FAM126B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Consensus CDS
    CCDS2335.1
    UniProtKB/Swiss-Prot
    Q8IXS8
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  5. NM_001321623.1NP_001308552.1  protein FAM126B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  6. NM_001321624.1NP_001308553.1  protein FAM126B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  7. NM_001321625.2NP_001308554.1  protein FAM126B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  8. NM_001321626.2NP_001308555.1  protein FAM126B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  9. NM_001321627.1NP_001308556.1  protein FAM126B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC005037, AL832346, BC039295, DA848582
    UniProtKB/Swiss-Prot
    Q8IXS8
    Conserved Domains (1) summary
    pfam09790
    Location:2248
    Hyccin; Hyccin
  10. NM_001321628.2NP_001308557.1  protein FAM126B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Conserved Domains (1) summary
    pfam09790
    Location:2248
    Hyccin; Hyccin
  11. NM_001321629.1NP_001308558.1  protein FAM126B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC005037, AC007272
    Conserved Domains (1) summary
    pfam09790
    Location:2248
    Hyccin; Hyccin
  12. NM_173822.5NP_776183.1  protein FAM126B isoform 1

    See identical proteins and their annotated locations for NP_776183.1

    Status: VALIDATED

    Source sequence(s)
    AC005037, AK097111, AK315104, BC039295, BC045174, DA848582
    Consensus CDS
    CCDS2335.1
    UniProtKB/Swiss-Prot
    Q8IXS8
    UniProtKB/TrEMBL
    B3KUG1
    Related
    ENSP00000393667.2, ENST00000418596.7
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    200973718..201071671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003879.1XP_016859368.1  protein FAM126B isoform X1

    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  2. XM_017003882.1XP_016859371.1  protein FAM126B isoform X3

    Conserved Domains (1) summary
    pfam09790
    Location:2248
    Hyccin; Hyccin
  3. XM_017003881.1XP_016859370.1  protein FAM126B isoform X2

    UniProtKB/Swiss-Prot
    Q8IXS8
    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  4. XM_017003883.1XP_016859372.1  protein FAM126B isoform X4

    Conserved Domains (1) summary
    pfam09790
    Location:2248
    Hyccin; Hyccin
  5. XM_006712443.3XP_006712506.1  protein FAM126B isoform X1

    See identical proteins and their annotated locations for XP_006712506.1

    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  6. XM_011511002.2XP_011509304.1  protein FAM126B isoform X1

    See identical proteins and their annotated locations for XP_011509304.1

    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
  7. XM_017003880.1XP_016859369.1  protein FAM126B isoform X1

    Conserved Domains (1) summary
    pfam09790
    Location:22330
    Hyccin; Hyccin
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