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IGHV4-31 immunoglobulin heavy variable 4-31 [ Homo sapiens (human) ]

Gene ID: 28396, updated on 14-May-2022

Summary

Official Symbol
IGHV4-31provided by HGNC
Official Full Name
immunoglobulin heavy variable 4-31provided by HGNC
Primary source
HGNC:HGNC:5649
See related
IMGT/GENE-DB:IGHV4-31; AllianceGenome:HGNC:5649
Gene type
other
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IGHV431
Summary
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
not in current annotation release
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Genomic context

See IGHV4-31 in Genome Data Viewer
Location:
14q32.33
Annotation release Status Assembly Chr Location
105 latest, but not current GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (106805207..106805644, complement)
105 latest, but not current HuRef (GCF_000002125.1) 14 AC_000146.1 (86942185..86942622, complement)
105 latest, but not current CHM1_1.1 (GCF_000306695.2) 14 NC_018925.2 (106686239..106686676, complement)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • anti-RhD monoclonal T125 gamma1 heavy chain

Clone Names

  • FLJ45507

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables antigen binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables immunoglobulin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in complement activation, classical pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in defense response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phagocytosis, engulfment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phagocytosis, recognition IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of B cell activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of immunoglobulin complex, circulating IBA
Inferred from Biological aspect of Ancestor
more info
PubMed