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UTS2R urotensin 2 receptor [ Homo sapiens (human) ]

Gene ID: 2837, updated on 1-Jun-2020

Summary

Official Symbol
UTS2Rprovided by HGNC
Official Full Name
urotensin 2 receptorprovided by HGNC
Primary source
HGNC:HGNC:4468
See related
Ensembl:ENSG00000181408 MIM:600896
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UTR; UTR2; GPR14; UR-2-R
Orthologs

Genomic context

See UTS2R in Genome Data Viewer
Location:
17q25.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (82371765..82377458)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (80330647..80333528)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene secreted and transmembrane 1 Neighboring gene testis expressed 19 Neighboring gene 2-oxoglutarate and iron dependent oxygenase domain containing 3 Neighboring gene hexosaminidase D Neighboring gene cytochrome b-245 chaperone 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled peptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
urotensin II receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway TAS
Traceable Author Statement
more info
 
blood circulation TAS
Traceable Author Statement
more info
PubMed 
neuropeptide signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of blood pressure IEA
Inferred from Electronic Annotation
more info
 
regulation of blood vessel diameter IEA
Inferred from Electronic Annotation
more info
 
signal transduction TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane TAS
Traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
urotensin-2 receptor
Names
G-protein coupled receptor 14
UR-II-R
urotensin II receptor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001381897.1NP_001368826.1  urotensin-2 receptor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC132938
  2. NM_018949.3NP_061822.1  urotensin-2 receptor

    See identical proteins and their annotated locations for NP_061822.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC132938
    Consensus CDS
    CCDS11810.1
    UniProtKB/Swiss-Prot
    Q9UKP6
    Related
    ENSP00000323516.2, ENST00000313135.3
    Conserved Domains (1) summary
    cd14999
    Location:53326
    7tmA_UII-R; urotensin-II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    82371765..82377458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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