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Atp5o ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit [ Mus musculus (house mouse) ]

Gene ID: 28080, updated on 5-Jan-2023

Summary

Official Symbol
Atp5oprovided by MGI
Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunitprovided by MGI
Primary source
MGI:MGI:106341
See related
Ensembl:ENSMUSG00000022956 AllianceGenome:MGI:106341
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ATPO; OSCP; Atp5po; D12Wsu28e
Summary
Predicted to enable estradiol binding activity. Predicted to contribute to ATP hydrolysis activity and proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in mitochondrial ATP synthesis coupled proton transport. Predicted to act upstream of or within ion transport. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; integumental system; and nervous system. Orthologous to human ATP5PO (ATP synthase peripheral stalk subunit OSCP). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 233.2), placenta adult (RPKM 134.9) and 28 other tissues See more
Orthologs
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Genomic context

See Atp5o in Genome Data Viewer
Location:
16; 16 C4
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (91722111..91728518, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (91925223..91931630, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene intersectin 1 (SH3 domain protein 1A) Neighboring gene predicted gene, 52262 Neighboring gene predicted gene, 25245 Neighboring gene RIKEN cDNA D430001F17 gene Neighboring gene predicted gene, 36797

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to ATP hydrolysis activity ISO
Inferred from Sequence Orthology
more info
 
enables estradiol binding ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to proton-transporting ATP synthase activity, rotational mechanism ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in ATP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in ATP metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
 
involved_in proton motive force-driven mitochondrial ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proton motive force-driven mitochondrial ATP synthesis ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ATP synthase subunit O, mitochondrial
Names
ATP synthase peripheral stalk subunit OSCP
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; DNA segment, Chr 12, Wayne State University 28, expressed
oligomycin sensitivity conferral protein
NP_613063.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138597.2NP_613063.1  ATP synthase subunit O, mitochondrial precursor

    See identical proteins and their annotated locations for NP_613063.1

    Status: PROVISIONAL

    Source sequence(s)
    AC126053
    Consensus CDS
    CCDS28331.1
    UniProtKB/Swiss-Prot
    Q9DB20
    Related
    ENSMUSP00000023677.4, ENSMUST00000023677.10
    Conserved Domains (1) summary
    pfam00213
    Location:37209
    OSCP; ATP synthase delta (OSCP) subunit

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    91722111..91728518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)