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CA4 carbonic anhydrase 4 [ Bos taurus (domestic cattle) ]

Gene ID: 280741, updated on 17-Aug-2024

Summary

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Official Symbol
CA4provided by VGNC
Official Full Name
carbonic anhydrase 4provided by VGNC
Primary source
VGNC:VGNC:26654
See related
BGD:BT11512; Ensembl:ENSBTAG00000017969
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (12804065..12811833, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 32 Neighboring gene V-type proton ATPase subunit G 3-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC132343008 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene zinc finger HIT-type containing 3 Neighboring gene myosin XIX

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
carbonic anhydrase 4
Names
CA-IV
carbonate dehydratase IV
carbonic anhydrase IV
NP_776322.1
XP_005220030.1
XP_024835300.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173897.1 → NP_776322.1  carbonic anhydrase 4 precursor

    See identical proteins and their annotated locations for NP_776322.1

    Status: PROVISIONAL

    Source sequence(s)
    U58870
    UniProtKB/Swiss-Prot
    A5PKL8, Q95323
    UniProtKB/TrEMBL
    A0A3Q1LST6
    Related
    ENSBTAP00000023909.6, ENSBTAT00000023909.7
    Conserved Domains (1) summary
    cd03117
    Location:49 → 283
    alpha_CA_IV_XV_like; Carbonic anhydrase alpha, CA_IV, CA_XV, like isozymes. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    12804065..12811833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005219973.3 → XP_005220030.1  carbonic anhydrase 4 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LST6, A0AAA9RTE0
    Related
    ENSBTAP00000076204.1, ENSBTAT00000104986.1
    Conserved Domains (1) summary
    cd03117
    Location:35 → 269
    alpha_CA_IV_XV_like; Carbonic anhydrase alpha, CA_IV, CA_XV, like isozymes. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

  2. XM_024979532.2 → XP_024835300.1  carbonic anhydrase 4 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LST6
    Conserved Domains (1) summary
    cd03117
    Location:89 → 323
    alpha_CA_IV_XV_like; Carbonic anhydrase alpha, CA_IV, CA_XV, like isozymes. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95323.1 GenPept UniProtKB/Swiss-Prot:Q95323

Gene LinkOut

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