Rrp9 ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rrp9provided by MGI
Official Full Name: ribosomal RNA processing 9, U3 small nucleolar RNA binding proteinprovided by MGI
Primary source: MGI:MGI:2384313
See related: Ensembl:ENSMUSG00000041506 AllianceGenome:MGI:2384313
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 55kDa; U3-55k; Rnu3ip2; D9Wsu10e
Summary: Predicted to enable U3 snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of box C/D methylation guide snoRNP complex and small-subunit processome. Is expressed in embryo and extraembryonic component. Orthologous to human RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in ovary adult (RPKM 15.7), thymus adult (RPKM 12.0) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 9 F1; 9 57.59 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (106354508..106362614)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (106477309..106485415)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

We cloned and sequenced the cDNAs of the mouse PARP-3 (Adprt3) gene encoding poly(ADP-ribose) polymerase 3 and of the closely linked U3-55k gene coding for the U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein.
Title: Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:224257

RH125696 (e-PCR)
- UniSTS:142814

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables U3 snoRNA binding	ISO Inferred from Sequence Orthology more info
enables U3 snoRNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables snoRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in rRNA processing	ISO Inferred from Sequence Orthology more info
involved_in rRNA processing	ISS Inferred from Sequence or Structural Similarity more info
involved_in ribosomal small subunit biogenesis	ISO Inferred from Sequence Orthology more info
involved_in ribosomal small subunit biogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of box C/D methylation guide snoRNP complex	IEA Inferred from Electronic Annotation more info
part_of box C/D methylation guide snoRNP complex	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISS Inferred from Sequence or Structural Similarity more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info
part_of small-subunit processome	ISO Inferred from Sequence Orthology more info
part_of small-subunit processome	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: U3 small nucleolar RNA-interacting protein 2

Names: RNA, U3 small nucleolar interacting protein 2; RRP9 homolog; RRP9, small subunit (SSU) processome component, homolog; U3 small nucleolar ribonucleoprotein-associated 55 kDa protein; U3 snoRNP-associated 55-kDa protein; U3 snoRNP-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_145620.4 → NP_663595.1 U3 small nucleolar RNA-interacting protein 2

See identical proteins and their annotated locations for NP_663595.1

Status: PROVISIONAL

Source sequence(s)

AC151729

Consensus CDS

CCDS23481.1

UniProtKB/Swiss-Prot

Q8CFB7, Q91WM3

Related

ENSMUSP00000038580.9, ENSMUST00000047721.10

Conserved Domains (3) summary

COG2319
Location:136 → 403

WD40; WD40 repeat [General function prediction only]

cd00200
Location:139 → 439

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:149 → 197

7WD40; WD40 repeat [structural motif]