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Aak1 AP2 associated kinase 1 [ Mus musculus (house mouse) ]

Gene ID: 269774, updated on 8-May-2024

Summary

Official Symbol
Aak1provided by MGI
Official Full Name
AP2 associated kinase 1provided by MGI
Primary source
MGI:MGI:1098687
See related
Ensembl:ENSMUSG00000057230 AllianceGenome:MGI:1098687
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm38495; mKIAA1048; 9630042K20; D6Ertd245e; 5530400K14Rik
Summary
Predicted to enable AP-2 adaptor complex binding activity; Notch binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including positive regulation of Notch signaling pathway; protein stabilization; and regulation of clathrin-dependent endocytosis. Predicted to act upstream of or within endocytosis and phosphorylation. Predicted to be located in cell leading edge and terminal bouton. Predicted to be part of clathrin complex. Predicted to be active in cytoplasm. Is expressed in cranial ganglion; dorsal root ganglion; retina nuclear layer; and telencephalon. Orthologous to human AAK1 (AP2 associated kinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 16.3), cortex adult (RPKM 15.4) and 24 other tissues See more
Orthologs
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Genomic context

See Aak1 in Genome Data Viewer
Location:
6 D1; 6 37.75 cM
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (86826252..86980209)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (86849274..87003227)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene germ cell-less, spermatogenesis associated 1 Neighboring gene STARR-positive B cell enhancer ABC_E3661 Neighboring gene annexin A4 Neighboring gene STARR-seq mESC enhancer starr_16540 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:86774247-86774356 Neighboring gene RIKEN cDNA 2610306M01 gene Neighboring gene STARR-positive B cell enhancer ABC_E6451 Neighboring gene STARR-positive B cell enhancer ABC_E9670 Neighboring gene STARR-positive B cell enhancer ABC_E8113 Neighboring gene STARR-seq mESC enhancer starr_16545 Neighboring gene STARR-positive B cell enhancer ABC_E6452 Neighboring gene NFU1 iron-sulfur cluster scaffold Neighboring gene STARR-seq mESC enhancer starr_16547 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:87025148-87025378 Neighboring gene glutamine fructose-6-phosphate transaminase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (3) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC40785

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables AP-2 adaptor complex binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables AP-2 adaptor complex binding ISO
Inferred from Sequence Orthology
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables Notch binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of Notch signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in presynaptic endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in presynaptic endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in presynaptic endocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of clathrin-dependent endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of clathrin-dependent endocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein localization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in calyx of Held ISO
Inferred from Sequence Orthology
more info
 
located_in cell leading edge ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
part_of clathrin complex ISO
Inferred from Sequence Orthology
more info
 
located_in clathrin-coated pit IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in presynapse IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in presynapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in presynapse ISO
Inferred from Sequence Orthology
more info
 
located_in synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in terminal bouton ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
AP2-associated protein kinase 1
Names
adaptor-associated kinase 1
NP_001035195.1
NP_001365581.1
NP_001365583.1
NP_001365584.1
NP_808430.2
XP_006506255.1
XP_017177086.1
XP_030111273.1
XP_030111275.1
XP_030111276.1
XP_030111278.1
XP_036022028.1
XP_036022029.1
XP_036022030.1
XP_036022031.1
XP_036022032.1
XP_036022033.1
XP_036022034.1
XP_036022035.1
XP_036022036.1
XP_036022037.1
XP_036022038.1
XP_036022039.1
XP_036022040.1
XP_036022041.1
XP_036022042.1
XP_036022043.1
XP_036022044.1
XP_036022045.1
XP_036022046.1
XP_036022047.1
XP_036022048.1
XP_036022049.1
XP_036022050.1
XP_036022051.1
XP_036022052.1
XP_036022053.1
XP_036022054.1
XP_036022055.1
XP_036022056.1
XP_036022057.1
XP_036022058.1
XP_036022059.1
XP_036022060.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040106.3NP_001035195.1  AP2-associated protein kinase 1 isoform 1

    See identical proteins and their annotated locations for NP_001035195.1

    Status: VALIDATED

    Source sequence(s)
    AC157099, AC159712
    Consensus CDS
    CCDS39544.1
    UniProtKB/Swiss-Prot
    B2RUJ0, Q3TY53, Q3UHJ0, Q6ZPZ6, Q80XP6
    Related
    ENSMUSP00000086948.7, ENSMUST00000089519.13
    Conserved Domains (2) summary
    smart00220
    Location:47307
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  2. NM_001378652.1NP_001365581.1  AP2-associated protein kinase 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC157099, AC159712
    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9101122
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  3. NM_001378654.1NP_001365583.1  AP2-associated protein kinase 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC157099, AC159712
    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9101122
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  4. NM_001378655.1NP_001365584.1  AP2-associated protein kinase 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC157099, AC159712
    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335541
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:8291041
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  5. NM_177762.7NP_808430.2  AP2-associated protein kinase 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC157099, AC159712
    Consensus CDS
    CCDS20317.1
    UniProtKB/Swiss-Prot
    Q3UHJ0
    Related
    ENSMUSP00000003710.10, ENSMUST00000003710.10
    Conserved Domains (2) summary
    smart00220
    Location:47307
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    86826252..86980209
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036166138.1XP_036022031.1  AP2-associated protein kinase 1 isoform X1

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10851297
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  2. XM_036166152.1XP_036022045.1  AP2-associated protein kinase 1 isoform X13

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335541
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9711183
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  3. XM_036166137.1XP_036022030.1  AP2-associated protein kinase 1 isoform X1

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10851297
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  4. XM_036166157.1XP_036022050.1  AP2-associated protein kinase 1 isoform X17

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9421154
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  5. XM_036166163.1XP_036022056.1  AP2-associated protein kinase 1 isoform X22

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335541
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:8291041
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  6. XM_036166165.1XP_036022058.1  AP2-associated protein kinase 1 isoform X27

    Conserved Domains (3) summary
    PHA03247
    Location:320693
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  7. XM_030255418.2XP_030111278.1  AP2-associated protein kinase 1 isoform X31

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335541
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  8. XM_036166136.1XP_036022029.1  AP2-associated protein kinase 1 isoform X1

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10851297
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  9. XM_036166149.1XP_036022042.1  AP2-associated protein kinase 1 isoform X10

    Conserved Domains (4) summary
    PHA03247
    Location:320693
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9771189
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  10. XM_036166146.1XP_036022039.1  AP2-associated protein kinase 1 isoform X8

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335542
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10041216
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  11. XM_036166139.1XP_036022032.1  AP2-associated protein kinase 1 isoform X2

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10841296
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  12. XM_006506192.3XP_006506255.1  AP2-associated protein kinase 1 isoform X24

    Conserved Domains (2) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  13. XM_036166135.1XP_036022028.1  AP2-associated protein kinase 1 isoform X1

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10851297
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  14. XM_036166144.1XP_036022037.1  AP2-associated protein kinase 1 isoform X7

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10111223
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  15. XM_036166141.1XP_036022034.1  AP2-associated protein kinase 1 isoform X4

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10511263
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  16. XM_036166148.1XP_036022041.1  AP2-associated protein kinase 1 isoform X10

    Conserved Domains (4) summary
    PHA03247
    Location:320693
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9771189
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  17. XM_036166155.1XP_036022048.1  AP2-associated protein kinase 1 isoform X16

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9431155
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  18. XM_036166140.1XP_036022033.1  AP2-associated protein kinase 1 isoform X3

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10531265
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  19. XM_036166143.1XP_036022036.1  AP2-associated protein kinase 1 isoform X6

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10191231
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  20. XM_036166153.1XP_036022046.1  AP2-associated protein kinase 1 isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:320693
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9451157
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  21. XM_036166158.1XP_036022051.1  AP2-associated protein kinase 1 isoform X18

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9111123
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  22. XM_030255416.2XP_030111276.1  AP2-associated protein kinase 1 isoform X27

    Conserved Domains (3) summary
    PHA03247
    Location:320693
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  23. XM_030255413.2XP_030111273.1  AP2-associated protein kinase 1 isoform X25

    Conserved Domains (3) summary
    PHA03247
    Location:320693
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  24. XM_036166147.1XP_036022040.1  AP2-associated protein kinase 1 isoform X9

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335541
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10031215
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  25. XM_017321597.2XP_017177086.1  AP2-associated protein kinase 1 isoform X29

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335541
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  26. XM_036166151.1XP_036022044.1  AP2-associated protein kinase 1 isoform X12

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335542
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9721184
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  27. XM_036166145.1XP_036022038.1  AP2-associated protein kinase 1 isoform X8

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335542
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10041216
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  28. XM_036166160.1XP_036022053.1  AP2-associated protein kinase 1 isoform X20

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335542
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:8621074
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  29. XM_036166159.1XP_036022052.1  AP2-associated protein kinase 1 isoform X19

    Conserved Domains (4) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335542
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:8641076
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  30. XM_036166167.1XP_036022060.1  AP2-associated protein kinase 1 isoform X30

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    PRK10263
    Location:335542
    PRK10263; DNA translocase FtsK; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  31. XM_036166162.1XP_036022055.1  AP2-associated protein kinase 1 isoform X21

    Conserved Domains (3) summary
    PHA03247
    Location:91464
    PHA03247; large tegument protein UL36; Provisional
    pfam15282
    Location:8561068
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
    cl21453
    Location:187
    PKc_like; Protein Kinases, catalytic domain
  32. XM_036166142.1XP_036022035.1  AP2-associated protein kinase 1 isoform X5

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:10501262
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  33. XM_036166150.1XP_036022043.1  AP2-associated protein kinase 1 isoform X11

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9761188
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  34. XM_036166156.1XP_036022049.1  AP2-associated protein kinase 1 isoform X17

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9421154
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  35. XM_036166154.1XP_036022047.1  AP2-associated protein kinase 1 isoform X15

    Conserved Domains (3) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
    pfam15282
    Location:9441156
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
  36. XM_036166161.1XP_036022054.1  AP2-associated protein kinase 1 isoform X21

    Conserved Domains (3) summary
    PHA03247
    Location:91464
    PHA03247; large tegument protein UL36; Provisional
    pfam15282
    Location:8561068
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
    cl21453
    Location:187
    PKc_like; Protein Kinases, catalytic domain
  37. XM_036166164.1XP_036022057.1  AP2-associated protein kinase 1 isoform X23

    Conserved Domains (2) summary
    pfam15282
    Location:775987
    BMP2K_C; BMP-2-inducible protein kinase C-terminus
    cl21453
    Location:187
    PKc_like; Protein Kinases, catalytic domain
  38. XM_030255415.2XP_030111275.1  AP2-associated protein kinase 1 isoform X26

    Conserved Domains (2) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases
  39. XM_036166166.1XP_036022059.1  AP2-associated protein kinase 1 isoform X28

    Conserved Domains (2) summary
    PHA03378
    Location:296429
    PHA03378; EBNA-3B; Provisional
    cd14037
    Location:42316
    STKc_NAK_like; Catalytic domain of Numb-Associated Kinase (NAK)-like Serine/Threonine kinases