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Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked [ Mus musculus (house mouse) ]

Gene ID: 26905, updated on 17-Nov-2020

Summary

Official Symbol
Eif2s3xprovided by MGI
Official Full Name
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linkedprovided by MGI
Primary source
MGI:MGI:1349431
See related
Ensembl:ENSMUSG00000035150
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Eif-2g; Eif-2gx; AA409828; AA547477; AI314668; eIF-2-gamma X
Expression
Ubiquitous expression in CNS E11.5 (RPKM 48.5), placenta adult (RPKM 48.0) and 27 other tissues See more
Orthologs

Genomic context

See Eif2s3x in Genome Data Viewer
Location:
X C3; X 41.52 cM
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (93232315..93256257, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (94188709..94212651, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (91434048..91457990, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6987 Neighboring gene zinc finger protein X-linked Neighboring gene predicted gene, 46691 Neighboring gene kelch-like 15 Neighboring gene microRNA 7673 Neighboring gene predicted gene 5400

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation factor activity, RNA binding ISO
Inferred from Sequence Orthology
more info
 
translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
formation of translation preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of translational fidelity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation IEA
Inferred from Electronic Annotation
more info
 
translational initiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
eukaryotic translation initiation factor 2 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
eukaryotic translation initiation factor 2 complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 2 subunit 3, X-linked
Names
eukaryotic translation initiation factor 2 subunit gamma, X-linked
NP_036140.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012010.3NP_036140.1  eukaryotic translation initiation factor 2 subunit 3, X-linked

    See identical proteins and their annotated locations for NP_036140.1

    Status: VALIDATED

    Source sequence(s)
    AL646049, AL646092
    Consensus CDS
    CCDS30277.1
    UniProtKB/Swiss-Prot
    Q9Z0N1
    UniProtKB/TrEMBL
    Q3TML6
    Related
    ENSMUSP00000059395.8, ENSMUST00000050328.14
    Conserved Domains (4) summary
    cd01888
    Location:42248
    eIF2_gamma; Gamma subunit of initiation factor 2 (eIF2 gamma)
    PTZ00327
    Location:13466
    PTZ00327; eukaryotic translation initiation factor 2 gamma subunit; Provisional
    cd03688
    Location:249362
    eIF2_gamma_II; Domain II of the gamma subunit of eukaryotic translation initiation factor 2
    cd15490
    Location:365459
    eIF2_gamma_III; Domain III of eukaryotic initiation factor eIF2 gamma

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    93232315..93256257 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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