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FAM169A family with sequence similarity 169 member A [ Homo sapiens (human) ]

Gene ID: 26049, updated on 5-Sep-2021

Summary

Official Symbol
FAM169Aprovided by HGNC
Official Full Name
family with sequence similarity 169 member Aprovided by HGNC
Primary source
HGNC:HGNC:29138
See related
Ensembl:ENSG00000198780 MIM:615769
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SLAP75
Expression
Broad expression in brain (RPKM 10.3), testis (RPKM 7.3) and 15 other tissues See more
Orthologs
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Genomic context

See FAM169A in Genome Data Viewer
Location:
5q13.3
Exon count:
15
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (74777574..74867994, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (74073399..74162791, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ectodermal-neural cortex 1 Neighboring gene hexosaminidase subunit beta Neighboring gene RNA, U6 small nuclear 658, pseudogene Neighboring gene GTP dependent ribosome recycling factor mitochondrial 2 Neighboring gene RNA, U6 small nuclear 1330, pseudogene Neighboring gene NSA2 ribosome biogenesis factor Neighboring gene actin related protein 2/3 complex subunit 1A pseudogene Neighboring gene uncharacterized LOC441086 Neighboring gene uncharacterized LOC105379039 Neighboring gene zinc finger protein 28 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0888

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
soluble lamin-associated protein of 75 kDa
Names
protein FAM169A
soluble lamina-associated protein of 75 kD

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001376049.1NP_001362978.1  soluble lamin-associated protein of 75 kDa isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214
  2. NM_001376050.1NP_001362979.1  soluble lamin-associated protein of 75 kDa isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214
  3. NM_001376051.1NP_001362980.1  soluble lamin-associated protein of 75 kDa isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214
  4. NM_001376052.1NP_001362981.1  soluble lamin-associated protein of 75 kDa isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214
  5. NM_001376053.1NP_001362982.1  soluble lamin-associated protein of 75 kDa isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214
  6. NM_001376054.1NP_001362983.1  soluble lamin-associated protein of 75 kDa isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214
  7. NM_015566.3NP_056381.1  soluble lamin-associated protein of 75 kDa isoform 1

    See identical proteins and their annotated locations for NP_056381.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and is protein-coding.
    Source sequence(s)
    AB020695, AC010501, AC093214, DA326879
    Consensus CDS
    CCDS43330.1
    UniProtKB/Swiss-Prot
    Q9Y6X4
    Related
    ENSP00000373808.4, ENST00000389156.9

RNA

  1. NR_046462.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an alternate 5'-most exon and lacks an internal exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC093214, AK022981, BX640902, DB024270
    Related
    ENST00000510609.5
  2. NR_164753.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214
  3. NR_164754.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC010501, AC093214

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    74777574..74867994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009332.1XP_016864821.1  soluble lamin-associated protein of 75 kDa isoform X2

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