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Fam169a family with sequence similarity 169, member A [ Mus musculus (house mouse) ]

Gene ID: 320557, updated on 8-Jan-2023

Summary

Official Symbol
Fam169aprovided by MGI
Official Full Name
family with sequence similarity 169, member Aprovided by MGI
Primary source
MGI:MGI:2444268
See related
Ensembl:ENSMUSG00000041817 AllianceGenome:MGI:2444268
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SLAP75; B230112C05Rik
Summary
Predicted to be located in membrane and nucleus. Is expressed in cerebellum external granule cell layer; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human FAM169A (family with sequence similarity 169 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 6.8), frontal lobe adult (RPKM 5.9) and 14 other tissues See more
Orthologs
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Genomic context

See Fam169a in Genome Data Viewer
Location:
13; 13 D1
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (97203795..97266801)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (97067287..97130293)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41027 Neighboring gene RIKEN cDNA 1700029F12 gene Neighboring gene predicted gene, 41028 Neighboring gene proteolipid protein 2 pseudogene Neighboring gene NSA2 ribosome biogenesis homolog Neighboring gene G elongation factor, mitochondrial 2 Neighboring gene hexosaminidase B Neighboring gene ectodermal-neural cortex 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
soluble lamin-associated protein of 75 kDa
Names
protein FAM169A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100458.1NP_001093928.1  soluble lamin-associated protein of 75 kDa

    See identical proteins and their annotated locations for NP_001093928.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK173051, AW123559, BG261627
    Consensus CDS
    CCDS49337.1
    UniProtKB/Swiss-Prot
    Q5XG69, Q69ZW7
    Related
    ENSMUSP00000043738.7, ENSMUST00000042517.8
    Conserved Domains (1) summary
    COG3144
    Location:337587
    FliK; Flagellar hook-length control protein FliK [Cell motility]
  2. NM_001146045.1NP_001139517.1  soluble lamin-associated protein of 75 kDa

    See identical proteins and their annotated locations for NP_001139517.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different segment for its 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK173051, AW123559, BC084589, CX734408
    Consensus CDS
    CCDS49337.1
    UniProtKB/Swiss-Prot
    Q5XG69, Q69ZW7
    Related
    ENSMUSP00000126209.2, ENSMUST00000169863.9
    Conserved Domains (1) summary
    COG3144
    Location:337587
    FliK; Flagellar hook-length control protein FliK [Cell motility]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    97203795..97266801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158070.1XP_036013963.1  soluble lamin-associated protein of 75 kDa isoform X3

  2. XM_030247298.2XP_030103158.1  soluble lamin-associated protein of 75 kDa isoform X3

  3. XM_030247299.2XP_030103159.1  soluble lamin-associated protein of 75 kDa isoform X4

  4. XM_030247297.2XP_030103157.1  soluble lamin-associated protein of 75 kDa isoform X2

  5. XM_006517686.4XP_006517749.1  soluble lamin-associated protein of 75 kDa isoform X1

    See identical proteins and their annotated locations for XP_006517749.1

    UniProtKB/Swiss-Prot
    Q5XG69, Q69ZW7
    Conserved Domains (1) summary
    COG3144
    Location:337587
    FliK; Flagellar hook-length control protein FliK [Cell motility]
  6. XM_011244669.3XP_011242971.1  soluble lamin-associated protein of 75 kDa isoform X1

    See identical proteins and their annotated locations for XP_011242971.1

    UniProtKB/Swiss-Prot
    Q5XG69, Q69ZW7
    Conserved Domains (1) summary
    COG3144
    Location:337587
    FliK; Flagellar hook-length control protein FliK [Cell motility]
  7. XM_036158069.1XP_036013962.1  soluble lamin-associated protein of 75 kDa isoform X1

    UniProtKB/Swiss-Prot
    Q69ZW7
    Conserved Domains (1) summary
    COG3144
    Location:337587
    FliK; Flagellar hook-length control protein FliK [Cell motility]
  8. XM_036158071.1XP_036013964.1  soluble lamin-associated protein of 75 kDa isoform X2