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GLIPR1L1 GLIPR1 like 1 [ Homo sapiens (human) ]

Gene ID: 256710, updated on 15-Jun-2019

Summary

Official Symbol
GLIPR1L1provided by HGNC
Official Full Name
GLIPR1 like 1provided by HGNC
Primary source
HGNC:HGNC:28392
See related
Ensembl:ENSG00000173401 MIM:610395
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRO7434; ALKN2972
Expression
Biased expression in testis (RPKM 4.4) and fat (RPKM 0.2) See more
Orthologs

Genomic context

See GLIPR1L1 in Genome Data Viewer
Location:
12q21.2
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 12 NC_000012.12 (75331834..75370390)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (75727550..75764170)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107983975 Neighboring gene cyclin G2 pseudogene 1 Neighboring gene calcyphosine 2 Neighboring gene necdin, MAGE family member pseudogene Neighboring gene GLIPR1 like 2 Neighboring gene GLI pathogenesis related 1 Neighboring gene KRR1 small subunit processome component homolog

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif downregulates the expression of GLI pathogenesis-related 1 like 1 (GLIPR1L1) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

General gene information

Homology

Clone Names

  • MGC26856

Gene Ontology Provided by GOA

Process Evidence Code Pubs
single fertilization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
acrosomal vesicle IEA
Inferred from Electronic Annotation
more info
 
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane raft IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
GLIPR1-like protein 1
Names
GLI pathogenesis related 1 like 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304964.2NP_001291893.1  GLIPR1-like protein 1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001291893.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC121761, AY358731, BC014603, BG196035
    Consensus CDS
    CCDS76578.1
    UniProtKB/Swiss-Prot
    Q6UWM5
    Related
    ENSP00000367967.4, ENST00000378695.8
    Conserved Domains (1) summary
    cd05385
    Location:32174
    SCP_GLIPR-1_like; SCP_GLIPR-1_like: SCP-like extracellular protein domain, glioma pathogenesis-related protein (GLIPR)-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich ...
  2. NM_152779.4NP_689992.1  GLIPR1-like protein 1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_689992.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1, and encodes a shorter isoform (2), compared to isoform 1.
    Source sequence(s)
    AC121761, AY358731, BC014603, BG196035
    Consensus CDS
    CCDS9009.1
    UniProtKB/Swiss-Prot
    Q6UWM5
    Related
    ENSP00000310770.2, ENST00000312442.2
    Conserved Domains (1) summary
    cd05385
    Location:32174
    SCP_GLIPR-1_like; SCP_GLIPR-1_like: SCP-like extracellular protein domain, glioma pathogenesis-related protein (GLIPR)-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    75331834..75370560
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019134.1XP_016874623.1  GLIPR1-like protein 1 isoform X2

  2. XM_011538134.3XP_011536436.2  GLIPR1-like protein 1 isoform X1

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