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ZNF318 zinc finger protein 318 [ Homo sapiens (human) ]

Gene ID: 24149, updated on 7-Oct-2018

Summary

Official Symbol
ZNF318provided by HGNC
Official Full Name
zinc finger protein 318provided by HGNC
Primary source
HGNC:HGNC:13578
See related
Ensembl:ENSG00000171467 MIM:617512; Vega:OTTHUMG00000014732
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TZF; ZFP318; HRIHFB2436
Expression
Broad expression in testis (RPKM 18.5), lymph node (RPKM 10.0) and 24 other tissues See more
Orthologs

Genomic context

See ZNF318 in Genome Data Viewer
Location:
6p21.1
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (43336070..43369443, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (43303808..43337181, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein L12 pseudogene 47 Neighboring gene cysteine rich protein 3 Neighboring gene ribosomal protein L34 pseudogene 14 Neighboring gene ribosomal protein S2 pseudogene 28 Neighboring gene uncharacterized LOC105375065 Neighboring gene ATP binding cassette subfamily C member 10 Neighboring gene microRNA 6780b

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Pathways from BioSystems

  • Androgen receptor signaling pathway, organism-specific biosystem (from WikiPathways)
    Androgen receptor signaling pathway, organism-specific biosystemAndrogens, mainly testosterone and 5alpha-dihydrotestosterone (DHT) play significant role in the growth and development of the male reproductive organs. These steroid hormones bring about their biolo...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: CRIP3

Homology

Clone Names

  • FLJ21852

Gene Ontology Provided by GOA

Function Evidence Code Pubs
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
zinc finger protein 318
Names
endocrine regulator
endocrine regulatory protein
testicular zinc finger

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014345.2NP_055160.2  zinc finger protein 318

    See identical proteins and their annotated locations for NP_055160.2

    Status: VALIDATED

    Source sequence(s)
    AK027061, AL583834, AL590383, BC098434
    Consensus CDS
    CCDS4895.2
    UniProtKB/Swiss-Prot
    Q5VUA4
    Related
    ENSP00000354964.2, OTTHUMP00000016436, ENST00000361428.2, OTTHUMT00000040601
    Conserved Domains (2) summary
    smart00451
    Location:11331167
    ZnF_U1; U1-like zinc finger
    cl19107
    Location:8671012
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

    Range
    43336070..43369443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011514451.2XP_011512753.1  zinc finger protein 318 isoform X1

    See identical proteins and their annotated locations for XP_011512753.1

    Conserved Domains (2) summary
    smart00451
    Location:953987
    ZnF_U1; U1-like zinc finger
    cl19107
    Location:687832
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
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