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FJX1 four-jointed box kinase 1 [ Homo sapiens (human) ]

Gene ID: 24147, updated on 1-Jun-2020

Summary

Official Symbol
FJX1provided by HGNC
Official Full Name
four-jointed box kinase 1provided by HGNC
Primary source
HGNC:HGNC:17166
See related
Ensembl:ENSG00000179431 MIM:612206
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene is the human ortholog of mouse and Drosophila four-jointed gene product. The Drosophila protein is important for growth and differentiation of legs and wings, and for proper development of the eyes. The exact function of this gene in humans is not known. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See FJX1 in Genome Data Viewer
Location:
11p13
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (35618460..35620865)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (35639735..35642421)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene SLC1A2 antisense RNA 1 Neighboring gene solute carrier family 1 member 2 Neighboring gene peptidase domain containing associated with muscle regeneration 1 Neighboring gene tripartite motif containing 44 Neighboring gene keratin 18 pseudogene 14

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22416, FLJ25593

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell-cell signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
retina layer formation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
four-jointed box protein 1
Names
four jointed box 1
four-jointed protein homolog
putative secreted ligand homologous to fjx1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014344.4NP_055159.2  four-jointed box protein 1 precursor

    See identical proteins and their annotated locations for NP_055159.2

    Status: REVIEWED

    Source sequence(s)
    AK026069, BC049171
    Consensus CDS
    CCDS44570.1
    UniProtKB/Swiss-Prot
    Q86VR8
    Related
    ENSP00000400223.1, ENST00000317811.6
    Conserved Domains (1) summary
    cd10468
    Location:149430
    Four-jointed-like_C; C-terminal kinase domain of Drosophila Four-jointed (Fj), mouse Fjx1, and related proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    35618460..35620865
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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