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Colec10 collectin sub-family member 10 [ Mus musculus (house mouse) ]

Gene ID: 239447, updated on 24-Apr-2022

Summary

Official Symbol
Colec10provided by MGI
Official Full Name
collectin sub-family member 10provided by MGI
Primary source
MGI:MGI:3606482
See related
Ensembl:ENSMUSG00000038591 AllianceGenome:MGI:3606482
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CL-L1
Summary
Enables mannose binding activity. Predicted to be involved in cranial skeletal system development. Predicted to be located in cytoplasm. Predicted to be part of collagen trimer. Predicted to be active in extracellular space. Is expressed in several structures, including extraembryonic component; gut; liver; musculature; and testis. Human ortholog(s) of this gene implicated in 3MC syndrome 3. Orthologous to human COLEC10 (collectin subfamily member 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver E18 (RPKM 6.6), placenta adult (RPKM 5.0) and 5 other tissues See more
Orthologs
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Genomic context

See Colec10 in Genome Data Viewer
Location:
15 D1; 15 21.15 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (54274170..54329755)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (54410774..54466360)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (54242329..54297913)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L19 pseudogene Neighboring gene predicted gene 5215 Neighboring gene ribosomal protein L19 pseudogene Neighboring gene ubiquitin-conjugating enzyme E2 C-like Neighboring gene mal, T cell differentiation protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC123727, MGC123950, MGC123951

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables chemoattractant activity ISO
Inferred from Sequence Orthology
more info
 
enables mannose binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol NAS
Non-traceable Author Statement
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
collectin-10
Names
collectin liver 1
collectin liver protein 1
collectin-L1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173422.3NP_775598.2  collectin-10 precursor

    See identical proteins and their annotated locations for NP_775598.2

    Status: VALIDATED

    Source sequence(s)
    AK028423, BC108945
    Consensus CDS
    CCDS27469.1
    UniProtKB/Swiss-Prot
    Q8CF98
    Related
    ENSMUSP00000037867.4, ENSMUST00000036737.4
    Conserved Domains (2) summary
    cd03591
    Location:157272
    CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
    pfam01391
    Location:4593
    Collagen; Collagen triple helix repeat (20 copies)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    54274170..54329755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245615.2XP_011243917.1  collectin-10 isoform X1

    See identical proteins and their annotated locations for XP_011243917.1

    Conserved Domains (1) summary
    cd03591
    Location:76191
    CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
  2. XM_011245616.3XP_011243918.1  collectin-10 isoform X1

    See identical proteins and their annotated locations for XP_011243918.1

    Conserved Domains (1) summary
    cd03591
    Location:76191
    CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)