U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 [ Mus musculus (house mouse) ]

Gene ID: 239318, updated on 11-Apr-2024

Summary

Official Symbol
Plcxd3provided by MGI
Official Full Name
phosphatidylinositol-specific phospholipase C, X domain containing 3provided by MGI
Primary source
MGI:MGI:2442605
See related
Ensembl:ENSMUSG00000049148 AllianceGenome:MGI:2442605
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B130016O10Rik
Summary
Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within lipid catabolic process and signal transduction. Is active in glutamatergic synapse. Is expressed in telencephalon. Orthologous to human PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 3.6), CNS E18 (RPKM 2.2) and 8 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Plcxd3 in Genome Data Viewer
Location:
15 A1; 15 1.96 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (4404973..4605067)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (4375491..4575585)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_37819 Neighboring gene predicted gene 2093 Neighboring gene 3-oxoacid CoA transferase 1 antisense RNA Neighboring gene 3-oxoacid CoA transferase 1 Neighboring gene STARR-seq mESC enhancer starr_37822 Neighboring gene STARR-seq mESC enhancer starr_37823 Neighboring gene STARR-seq mESC enhancer starr_37824 Neighboring gene STARR-seq mESC enhancer starr_37825 Neighboring gene STARR-seq mESC enhancer starr_37827 Neighboring gene STARR-seq mESC enhancer starr_37828 Neighboring gene STARR-seq mESC enhancer starr_37829 Neighboring gene STARR-seq mESC enhancer starr_37830 Neighboring gene STARR-seq mESC enhancer starr_37831 Neighboring gene STARR-seq mESC enhancer starr_37832 Neighboring gene STARR-seq mESC enhancer starr_37833 Neighboring gene STARR-seq mESC enhancer starr_37834 Neighboring gene STARR-seq mESC enhancer starr_37835 Neighboring gene STARR-seq mESC enhancer starr_37836 Neighboring gene STARR-seq mESC enhancer starr_37837 Neighboring gene complement component 6 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphoric diester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in glutamatergic synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
PI-PLC X domain-containing protein 3

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177355.3NP_796329.2  PI-PLC X domain-containing protein 3

    See identical proteins and their annotated locations for NP_796329.2

    Status: VALIDATED

    Source sequence(s)
    AC113957, AK038575, AK044972, BE945500
    Consensus CDS
    CCDS27362.2
    UniProtKB/Swiss-Prot
    Q8BLJ3, Q8BYR3
    UniProtKB/TrEMBL
    G3X9A7
    Related
    ENSMUSP00000053553.5, ENSMUST00000061925.5
    Conserved Domains (1) summary
    cd08616
    Location:19311
    PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    4404973..4605067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)