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Gmcl1 germ cell-less, spermatogenesis associated 1 [ Mus musculus (house mouse) ]

Gene ID: 23885, updated on 1-Mar-2024

Summary

Official Symbol
Gmcl1provided by MGI
Official Full Name
germ cell-less, spermatogenesis associated 1provided by MGI
Primary source
MGI:MGI:1345156
See related
Ensembl:ENSMUSG00000001157 AllianceGenome:MGI:1345156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DIP; Gcl; Gcl-1; glc-1; Btbd13; mglc-1; 2810049L19Rik
Summary
Acts upstream of or within regulation of transcription, DNA-templated. Located in nuclear envelope and nuclear matrix. Is expressed in several structures, including eye; genitourinary system; hemolymphoid system gland; liver; and lung. Orthologous to several human genes including GMCL1 (germ cell-less 1, spermatogenesis associated). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 18.2), CNS E14 (RPKM 8.7) and 27 other tissues See more
Orthologs
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Genomic context

See Gmcl1 in Genome Data Viewer
Location:
6 D1; 6 37.75 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (86668750..86710377, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (86691768..86733395, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E860 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:86634487-86634670 Neighboring gene MAX dimerization protein 1 Neighboring gene small nuclear ribonucleoprotein 27 (U4/U6.U5) Neighboring gene STARR-positive B cell enhancer ABC_E3661 Neighboring gene annexin A4 Neighboring gene STARR-seq mESC enhancer starr_16540 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:86774247-86774356 Neighboring gene RIKEN cDNA 2610306M01 gene Neighboring gene STARR-positive B cell enhancer ABC_E6451 Neighboring gene AP2 associated kinase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear matrix IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
germ cell-less protein-like 1
Names
DP-interacting protein
germ cell-less homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011818.3NP_035948.3  germ cell-less protein-like 1

    See identical proteins and their annotated locations for NP_035948.3

    Status: VALIDATED

    Source sequence(s)
    AF163665, AK004716, CJ122611, CX567687
    Consensus CDS
    CCDS20316.1
    UniProtKB/Swiss-Prot
    Q920G9, Q9DBW5, Q9QUP6
    UniProtKB/TrEMBL
    Q3UID6
    Related
    ENSMUSP00000001185.8, ENSMUST00000001185.14
    Conserved Domains (3) summary
    smart00225
    Location:107206
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:211281
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:96203
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    86668750..86710377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506056.4XP_006506119.1  germ cell-less protein-like 1 isoform X1

    Conserved Domains (1) summary
    cl28903
    Location:145
    BACK; BACK (BTB and C-terminal Kelch) domain

RNA

  1. XR_377446.4 RNA Sequence

  2. XR_003956194.1 RNA Sequence