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Ets2 E26 avian leukemia oncogene 2, 3' domain [ Mus musculus (house mouse) ]

Gene ID: 23872, updated on 8-Oct-2018

Summary

Official Symbol
Ets2provided by MGI
Official Full Name
E26 avian leukemia oncogene 2, 3' domainprovided by MGI
Primary source
MGI:MGI:95456
See related
Ensembl:ENSMUSG00000022895 Vega:OTTMUSG00000027024
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ets-2; AU022856
Expression
Ubiquitous expression in thymus adult (RPKM 84.5), lung adult (RPKM 48.0) and 27 other tissues See more
Orthologs

Genomic context

See Ets2 in Genome Data Viewer
Location:
16 C4; 16 56.64 cM
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (95702407..95721049)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (95924014..95942656)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31901 Neighboring gene predicted gene, 31989 Neighboring gene predicted gene 6599 Neighboring gene predicted gene, 32130 Neighboring gene predicted gene, 41509

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (6)  1 citation
  • Chemically induced (ENU) (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ectodermal cell fate commitment IGI
Inferred from Genetic Interaction
more info
PubMed 
mesoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
primitive streak formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011809.3NP_035939.3  protein C-ets-2

    See identical proteins and their annotated locations for NP_035939.3

    Status: VALIDATED

    Source sequence(s)
    AK038348, BE134375, BY140250
    Consensus CDS
    CCDS37412.1
    UniProtKB/Swiss-Prot
    P15037
    UniProtKB/TrEMBL
    Q3UP99
    Related
    ENSMUSP00000023612.8, OTTMUSP00000033528, ENSMUST00000023612.16, OTTMUST00000066803
    Conserved Domains (2) summary
    cd08543
    Location:85173
    SAM_PNT-ETS-2; Sterile alpha motif (SAM)/Pointed domain of ETS-2
    smart00413
    Location:361445
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

    Range
    95702407..95721049
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 129S6/SvEvTac

Genomic

  1. NT_039634.4 Reference GRCm38.p4 129S6/SvEvTac

    Range
    1572786..1591605
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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