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Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1 [ Mus musculus (house mouse) ]

Gene ID: 237858, updated on 12-May-2024

Summary

Official Symbol
Trarg1provided by MGI
Official Full Name
trafficking regulator of GLUT4 (SLC2A4) 1provided by MGI
Primary source
MGI:MGI:3029307
See related
Ensembl:ENSMUSG00000046275 AllianceGenome:MGI:3029307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DSPB1; Lost1; Tusc5; C130069F04Rik
Summary
Involved in endosome to plasma membrane protein transport and glucose import in response to insulin stimulus. Acts upstream of or within vesicle fusion to plasma membrane. Located in cytoplasmic vesicle membrane; perinuclear region of cytoplasm; and plasma membrane. Is expressed in dorsal root ganglion; lung; trigeminal ganglion; and white fat. Orthologous to human TRARG1 (trafficking regulator of GLUT4 (SLC2A4) 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in subcutaneous fat pad adult (RPKM 33.0), genital fat pad adult (RPKM 17.9) and 3 other tissues See more
Orthologs
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Genomic context

See Trarg1 in Genome Data Viewer
Location:
11 B5; 11 45.98 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (76570699..76589490)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (76679873..76698664)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46288 Neighboring gene basic helix-loop-helix family, member a9 Neighboring gene STARR-positive B cell enhancer ABC_E9829 Neighboring gene golgi SNAP receptor complex member 1 Neighboring gene STARR-positive B cell enhancer ABC_E3977 Neighboring gene carboxypeptidase D Neighboring gene predicted gene, 53688

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5) 
  • Targeted (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
trafficking regulator of GLUT4 1
Names
dispanin subfamily B member 1
tumor suppressor candidate 5 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177709.3NP_808377.1  trafficking regulator of GLUT4 1

    See identical proteins and their annotated locations for NP_808377.1

    Status: VALIDATED

    Source sequence(s)
    AK048522, AK158395, BX000359
    Consensus CDS
    CCDS25069.1
    UniProtKB/Swiss-Prot
    Q8C838
    Related
    ENSMUSP00000061634.3, ENSMUST00000062024.3
    Conserved Domains (1) summary
    pfam04505
    Location:98137
    CD225; Interferon-induced transmembrane protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    76570699..76589490
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)