Format

Send to:

Choose Destination

CARHSP1 calcium regulated heat stable protein 1 [ Homo sapiens (human) ]

Gene ID: 23589, updated on 21-Dec-2019

Summary

Official Symbol
CARHSP1provided by HGNC
Official Full Name
calcium regulated heat stable protein 1provided by HGNC
Primary source
HGNC:HGNC:17150
See related
Ensembl:ENSG00000153048 MIM:616885
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CSDC1; CRHSP24; CRHSP-24
Expression
Ubiquitous expression in testis (RPKM 17.9), adrenal (RPKM 11.8) and 25 other tissues See more
Orthologs

Genomic context

See CARHSP1 in Genome Data Viewer
Location:
16p13.2
Exon count:
12
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (8852942..8869012, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (8946799..8962869, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene transmembrane protein 186 Neighboring gene phosphomannomutase 2 Neighboring gene uncharacterized LOC100130283 Neighboring gene LITAF domain containing Neighboring gene ubiquitin specific peptidase 7 Neighboring gene uncharacterized LOC105371074

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC111446

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity, RNA polymerase II-specific ISM
Inferred from Sequence Model
more info
PubMed 
mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
PubMed 
phosphatase binding NAS
Non-traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
intracellular signal transduction TAS
Traceable Author Statement
more info
PubMed 
regulation of mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of mRNA stability ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
P granule ISS
Inferred from Sequence or Structural Similarity
more info
 
P-body IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with cytoplasmic exosome (RNase complex) ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
calcium-regulated heat-stable protein 1
Names
calcium regulated heat stable protein 1, 24kDa
calcium-regulated heat-stable protein (24kD)
calcium-regulated heat-stable protein of 24 kDa

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042476.2NP_001035941.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001035941.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BC001333, BQ004670, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000379838.2, ENST00000396593.6
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  2. NM_001278260.1NP_001265189.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001265189.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BQ004670, DB101255, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000481550.1, ENST00000611932.4
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  3. NM_001278261.1NP_001265190.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001265190.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BQ004670, DA736976, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000483591.1, ENST00000618335.4
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  4. NM_001278262.1NP_001265191.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001265191.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BQ004670, DB446945, HY005510, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000480542.1, ENST00000614449.4
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  5. NM_001278263.1NP_001265192.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001265192.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BM920489, BQ004670, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000455284.1, ENST00000561530.5
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  6. NM_001278264.1NP_001265193.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001265193.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BM693675, BQ004670, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000480144.1, ENST00000619881.4
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  7. NM_001278265.1NP_001265194.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001265194.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BQ004670, HY005510, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000478055.1, ENST00000610831.4
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  8. NM_001278266.1NP_001265195.1  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_001265195.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167, BQ004670, HY005510, HY090855
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000455855.1, ENST00000567554.5
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  9. NM_014316.4NP_055131.2  calcium-regulated heat-stable protein 1

    See identical proteins and their annotated locations for NP_055131.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript. Variants 1-9 encode the same protein.
    Source sequence(s)
    AC022167
    Consensus CDS
    CCDS10537.1
    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000311847.4, ENST00000311052.10
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    8852942..8869012 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011522444.2XP_011520746.1  calcium-regulated heat-stable protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011520746.1

    UniProtKB/Swiss-Prot
    Q9Y2V2
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
  2. XM_005255228.4XP_005255285.3  calcium-regulated heat-stable protein 1 isoform X1

  3. XM_005255229.5XP_005255286.1  calcium-regulated heat-stable protein 1 isoform X2

    See identical proteins and their annotated locations for XP_005255286.1

    UniProtKB/Swiss-Prot
    Q9Y2V2
    Related
    ENSP00000455522.1, ENST00000567908.5
    Conserved Domains (1) summary
    cd04458
    Location:63128
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
Support Center