U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gk5 glycerol kinase 5 [ Mus musculus (house mouse) ]

Gene ID: 235533, updated on 12-May-2024

Summary

Official Symbol
Gk5provided by MGI
Official Full Name
glycerol kinase 5provided by MGI
Primary source
MGI:MGI:2443336
See related
Ensembl:ENSMUSG00000041440 AllianceGenome:MGI:2443336
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C330018K18Rik; G630067D24Rik
Summary
Predicted to enable glycerol kinase activity. Predicted to be involved in several processes, including glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Predicted to be active in mitochondrion. Is expressed in olfactory epithelium and submandibular gland primordium. Orthologous to human GK5 (glycerol kinase 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in genital fat pad adult (RPKM 2.4), limb E14.5 (RPKM 1.9) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Gk5 in Genome Data Viewer
Location:
9 E3.3; 9 50.31 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (96001379..96066680)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (96119344..96184627)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene ataxia telangiectasia and Rad3 related Neighboring gene STARR-positive B cell enhancer ABC_E3852 Neighboring gene predicted gene, 16794 Neighboring gene STARR-positive B cell enhancer ABC_E8307 Neighboring gene STARR-seq mESC enhancer starr_24940 Neighboring gene 5'-3' exoribonuclease 1 Neighboring gene STARR-seq mESC enhancer starr_24941 Neighboring gene STARR-seq mESC enhancer starr_24942 Neighboring gene STARR-positive B cell enhancer ABC_E8308 Neighboring gene STARR-seq mESC enhancer starr_24949 Neighboring gene transcription factor Dp 2 Neighboring gene predicted gene, 39408 Neighboring gene ATPase, Na+/K+ transporting, beta 3 polypeptide

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables glycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glycerol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glycerol-3-phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in triglyceride metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
putative glycerol kinase 5
Names
ATP:glycerol 3-phosphotransferase 5
GK 5
glycerokinase 5
glycerol kinase 5 (putative)
NP_001355808.1
NP_796326.1
XP_006511195.1
XP_006511196.1
XP_006511197.1
XP_036010805.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368879.1NP_001355808.1  putative glycerol kinase 5 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC166175
    Consensus CDS
    CCDS90642.1
    UniProtKB/Swiss-Prot
    Q14B67, Q3TK02, Q3TSE0, Q80VA9, Q8BX05
    Related
    ENSMUSP00000082313.6, ENSMUST00000085217.12
    Conserved Domains (1) summary
    cd07793
    Location:25527
    FGGY_GK5_metazoa; metazoan glycerol kinase 5-like proteins; belongs to the FGGY family of carbohydrate kinases
  2. NM_177352.5NP_796326.1  putative glycerol kinase 5 isoform 2

    See identical proteins and their annotated locations for NP_796326.1

    Status: VALIDATED

    Source sequence(s)
    AC166175
    Consensus CDS
    CCDS52891.1
    UniProtKB/Swiss-Prot
    Q8BX05
    Related
    ENSMUSP00000112717.2, ENSMUST00000122383.3
    Conserved Domains (2) summary
    cd07793
    Location:25512
    FGGY_GK5_metazoa; metazoan glycerol kinase 5-like proteins; belongs to the FGGY family of carbohydrate kinases
    COG0554
    Location:20507
    GlpK; Glycerol kinase [Energy production and conversion]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    96001379..96066680
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154912.1XP_036010805.1  putative glycerol kinase 5 isoform X4

    Conserved Domains (1) summary
    cl17037
    Location:5388
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  2. XM_006511132.4XP_006511195.1  putative glycerol kinase 5 isoform X1

    Conserved Domains (1) summary
    cl17037
    Location:1437
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  3. XM_006511133.3XP_006511196.1  putative glycerol kinase 5 isoform X2

    Conserved Domains (1) summary
    cl17037
    Location:13430
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  4. XM_006511134.2XP_006511197.1  putative glycerol kinase 5 isoform X3

    Conserved Domains (1) summary
    cl17037
    Location:15424
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RNA

  1. XR_004935424.1 RNA Sequence