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Ddx19b DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b [ Mus musculus (house mouse) ]

Gene ID: 234733, updated on 5-Jun-2018
Official Symbol
Ddx19bprovided by MGI
Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19bprovided by MGI
Primary source
MGI:MGI:2148251
See related
Ensembl:ENSMUSG00000033658 Vega:OTTMUSG00000031896
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AW260119; 2810457M08Rik; 4921519L13Rik
Expression
Ubiquitous expression in testis adult (RPKM 17.0), CNS E11.5 (RPKM 7.1) and 26 other tissues See more
See Ddx19b in Genome Data Viewer
Location:
8; 8 E1
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (111003186..111031751, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (113527088..113551664, complement)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 2 Neighboring gene predicted gene, 39251 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a Neighboring gene microRNA 3473d Neighboring gene alanyl-tRNA synthetase Neighboring gene exosome component 6 Neighboring gene predicted gene, 38523 Neighboring gene nuclear encoded tRNA glycine 2 (anticodon GCC)

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
ATP-dependent RNA helicase DDX19B
NP_001177715.1
NP_001177729.1
NP_758488.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190786.1NP_001177715.1  ATP-dependent RNA helicase DDX19B isoform 1

    See identical proteins and their annotated locations for NP_001177715.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AK033235, AK147499, BC079644
    Consensus CDS
    CCDS57645.1
    UniProtKB/TrEMBL
    Q8BZY3, Q8R3C7
    Related
    ENSMUSP00000066806.5, OTTMUSP00000042137, ENSMUST00000065784.5, OTTMUST00000079073
    Conserved Domains (3) summary
    PTZ00424
    Location:106484
    PTZ00424; helicase 45; Provisional
    cd00079
    Location:322457
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cl21455
    Location:109311
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_001190800.1NP_001177729.1  ATP-dependent RNA helicase DDX19B isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at an alternate start codon, and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (3) has distinct N- and C-termini and is shorter than isoform 1.
    Source sequence(s)
    AC093451, AK013362, AK147499, BC079644
    UniProtKB/TrEMBL
    Q8R3C7
    Conserved Domains (3) summary
    smart00487
    Location:107310
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:307442
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cl21455
    Location:94296
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. NM_172284.5NP_758488.1  ATP-dependent RNA helicase DDX19B isoform 2

    See identical proteins and their annotated locations for NP_758488.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC093451, AK147499, BC079644
    Consensus CDS
    CCDS22669.1
    UniProtKB/TrEMBL
    Q8R3C7
    Related
    ENSMUSP00000038551.8, OTTMUSP00000042136, ENSMUST00000040241.14, OTTMUST00000079072
    Conserved Domains (3) summary
    PTZ00424
    Location:91469
    PTZ00424; helicase 45; Provisional
    cd00079
    Location:307442
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cl21455
    Location:94296
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

    Range
    111003186..111031751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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