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Adprhl1 ADP-ribosylhydrolase like 1 [ Mus musculus (house mouse) ]

Gene ID: 234072, updated on 30-Apr-2024

Summary

Official Symbol
Adprhl1provided by MGI
Official Full Name
ADP-ribosylhydrolase like 1provided by MGI
Primary source
MGI:MGI:2442168
See related
Ensembl:ENSMUSG00000031448 AllianceGenome:MGI:2442168
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arh2; Gm34595; D330008N11Rik
Summary
Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Orthologous to human ADPRHL1 (ADP-ribosylhydrolase like 1). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
Expression
Restricted expression toward heart adult (RPKM 27.0) See more
Orthologs
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Genomic context

See Adprhl1 in Genome Data Viewer
Location:
8; 8 A1.1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (13268449..13304079, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (13218788..13254542, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene GH regulated TBC protein 1 Neighboring gene RIKEN cDNA 2810030D12 gene Neighboring gene microRNA 1968 Neighboring gene STARR-seq mESC enhancer starr_20764 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:13213467-13213836 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:13213972-13214173 Neighboring gene defective in cullin neddylation 1 domain containing 2 Neighboring gene predicted gene, 25014 Neighboring gene transmembrane and coiled-coil domains 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ADP-ribosylarginine hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein de-ADP-ribosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
inactive ADP-ribosyltransferase ARH2
Names
ADP-ribosylhydrolase 2
ADP-ribosylhydrolase-like protein 1
[Protein ADP-ribosylarginine] hydrolase-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001409003.1NP_001395932.1  inactive ADP-ribosyltransferase ARH2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC130818, AC133520
  2. NM_001409005.1NP_001395934.1  inactive ADP-ribosyltransferase ARH2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC130818, AC133520
    UniProtKB/TrEMBL
    A0A0N4SVK8
    Related
    ENSMUSP00000145145.2, ENSMUST00000204916.3
  3. NM_172750.5NP_766338.1  inactive ADP-ribosyltransferase ARH2 isoform 1

    See identical proteins and their annotated locations for NP_766338.1

    Status: VALIDATED

    Source sequence(s)
    AC130818, AC133520
    Consensus CDS
    CCDS22108.1
    UniProtKB/Swiss-Prot
    Q8BGK2, Q8C4L0
    Related
    ENSMUSP00000033825.5, ENSMUST00000033825.11
    Conserved Domains (1) summary
    pfam03747
    Location:6326
    ADP_ribosyl_GH; ADP-ribosylglycohydrolase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    13268449..13304079 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154454.1XP_036010347.1  inactive ADP-ribosyltransferase ARH2 isoform X1