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Bud31 BUD31 homolog [ Mus musculus (house mouse) ]

Gene ID: 231889, updated on 11-Apr-2024

Summary

Official Symbol
Bud31provided by MGI
Official Full Name
BUD31 homologprovided by MGI
Primary source
MGI:MGI:2141291
See related
Ensembl:ENSMUSG00000038722 AllianceGenome:MGI:2141291
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G10; EDG2; EDG-2
Summary
Predicted to enable nuclear receptor binding activity and nuclear receptor coactivator activity. Predicted to be involved in mRNA splicing, via spliceosome and positive regulation of androgen receptor activity. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 2 spliceosome. Predicted to colocalize with chromatin. Is expressed in genitourinary system. Orthologous to human BUD31 (BUD31 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 80.7), placenta adult (RPKM 42.8) and 28 other tissues See more
Orthologs
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Genomic context

Location:
5 G2; 5 85.05 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (145077186..145084888)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (145140376..145148078)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:145877013-145877196 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:145877310-145877463 Neighboring gene STARR-positive B cell enhancer ABC_E11730 Neighboring gene actin related protein 2/3 complex, subunit 1B Neighboring gene PDGFA associated protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E8091 Neighboring gene pentatricopeptide repeat domain 1 Neighboring gene STARR-positive B cell enhancer ABC_E6397 Neighboring gene cleavage and polyadenylation specific factor 4 Neighboring gene ATP synthase membrane subunit f

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables nuclear receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables nuclear receptor coactivator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of androgen receptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of U2-type catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein BUD31 homolog
Names
maternal G10 transcript
protein G10 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008705.2NP_001008705.1  protein BUD31 homolog isoform 2

    See identical proteins and their annotated locations for NP_001008705.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AA051275, BC057025, BP770669
    Consensus CDS
    CCDS19857.1
    UniProtKB/Swiss-Prot
    Q6PGH1
    Related
    ENSMUSP00000125590.2, ENSMUST00000162308.8
    Conserved Domains (1) summary
    pfam01125
    Location:1102
    G10; G10 protein
  2. NM_001310770.1NP_001297699.1  protein BUD31 homolog isoform 1

    See identical proteins and their annotated locations for NP_001297699.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AC127411, BP770669, BX520786, CX567360
    Consensus CDS
    CCDS80463.1
    UniProtKB/Swiss-Prot
    E0CX20, Q6PGH1
    Related
    ENSMUSP00000125564.2, ENSMUST00000160075.2
    Conserved Domains (1) summary
    pfam01125
    Location:1143
    G10; G10 protein
  3. NM_001310771.1NP_001297700.1  protein BUD31 homolog isoform 1

    See identical proteins and their annotated locations for NP_001297700.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AA051275, BP770669, CJ044770, CJ047068, CX567360
    Consensus CDS
    CCDS80463.1
    UniProtKB/Swiss-Prot
    E0CX20, Q6PGH1
    Related
    ENSMUSP00000125738.2, ENSMUST00000162594.8
    Conserved Domains (1) summary
    pfam01125
    Location:1143
    G10; G10 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    145077186..145084888
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)