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BUD31 BUD31 homolog [ Homo sapiens (human) ]

Gene ID: 8896, updated on 5-Apr-2020

Summary

Official Symbol
BUD31provided by HGNC
Official Full Name
BUD31 homologprovided by HGNC
Primary source
HGNC:HGNC:29629
See related
Ensembl:ENSG00000106245 MIM:603477
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W
Expression
Ubiquitous expression in testis (RPKM 25.3), bone marrow (RPKM 23.9) and 25 other tissues See more
Orthologs

Genomic context

See BUD31 in Genome Data Viewer
Location:
7q22.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (99408641..99419616)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (99006243..99017239)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 4482 Neighboring gene actin related protein 2/3 complex subunit 1B Neighboring gene PDGFA associated protein 1 Neighboring gene microRNA 12119 Neighboring gene ATP5MF-PTCD1 readthrough Neighboring gene pentatricopeptide repeat domain 1 Neighboring gene SAP domain containing ribonucleoprotein pseudogene Neighboring gene cleavage and polyadenylation specific factor 4 Neighboring gene ATP synthase membrane subunit f

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
retropepsin gag-pol Positional proteomics analysis identifies the cleavage of human BUD31 homolog (S. cerevisiae) (BUD31) at amino acid residues 17-18 by the HIV-1 protease PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC111202

Gene Ontology Provided by GOA

Function Evidence Code Pubs
nuclear hormone receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
nuclear receptor transcription coactivator activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA splicing, via spliceosome IDA
Inferred from Direct Assay
more info
PubMed 
mRNA splicing, via spliceosome TAS
Traceable Author Statement
more info
 
positive regulation of androgen receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of nucleic acid-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
U2-type catalytic step 2 spliceosome IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with nuclear chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein BUD31 homolog
Names
G10 maternal transcript homolog
functional spliceosome-associated protein 17
maternal G10 transcript
protein EDG-2
protein G10 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370407.1NP_001357336.1  protein BUD31 homolog

    Status: VALIDATED

    Source sequence(s)
    AC004922
    Related
    ENSP00000386023.2, ENST00000403633.6
    Conserved Domains (1) summary
    pfam01125
    Location:1143
    G10; G10 protein
  2. NM_001370410.1NP_001357339.1  protein BUD31 homolog

    Status: VALIDATED

    Source sequence(s)
    AC004922
    Conserved Domains (1) summary
    pfam01125
    Location:1143
    G10; G10 protein
  3. NM_003910.4NP_003901.2  protein BUD31 homolog

    See identical proteins and their annotated locations for NP_003901.2

    Status: VALIDATED

    Source sequence(s)
    AC004922, BC022821
    Consensus CDS
    CCDS5663.1
    UniProtKB/Swiss-Prot
    P41223
    Related
    ENSP00000222969.5, ENST00000222969.10
    Conserved Domains (1) summary
    pfam01125
    Location:1143
    G10; G10 protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    99408641..99419616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005250671.5XP_005250728.1  protein BUD31 homolog isoform X1

    See identical proteins and their annotated locations for XP_005250728.1

    UniProtKB/Swiss-Prot
    P41223
    Conserved Domains (1) summary
    pfam01125
    Location:2134
    G10; G10 protein
  2. XM_017012760.2XP_016868249.1  protein BUD31 homolog isoform X1

    UniProtKB/Swiss-Prot
    P41223
    Conserved Domains (1) summary
    pfam01125
    Location:2134
    G10; G10 protein
  3. XM_005250670.5XP_005250727.1  protein BUD31 homolog isoform X1

    See identical proteins and their annotated locations for XP_005250727.1

    UniProtKB/Swiss-Prot
    P41223
    Conserved Domains (1) summary
    pfam01125
    Location:2134
    G10; G10 protein
  4. XM_017012761.2XP_016868250.1  protein BUD31 homolog isoform X1

    UniProtKB/Swiss-Prot
    P41223
    Conserved Domains (1) summary
    pfam01125
    Location:2134
    G10; G10 protein
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