U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Paqr3 progestin and adipoQ receptor family member III [ Mus musculus (house mouse) ]

Gene ID: 231474, updated on 8-Feb-2024

Summary

Official Symbol
Paqr3provided by MGI
Official Full Name
progestin and adipoQ receptor family member IIIprovided by MGI
Primary source
MGI:MGI:2679683
See related
Ensembl:ENSMUSG00000055725 AllianceGenome:MGI:2679683
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RKTG; 6330415A20Rik
Summary
Predicted to enable signaling receptor activity. Acts upstream of or within negative regulation of MAP kinase activity. Predicted to be located in Golgi apparatus. Orthologous to human PAQR3 (progestin and adipoQ receptor family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 5.7), whole brain E14.5 (RPKM 5.6) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Paqr3 in Genome Data Viewer
Location:
5 E3; 5 47.29 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (97229223..97259608, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (97081364..97111749, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46916 Neighboring gene STARR-positive B cell enhancer ABC_E11294 Neighboring gene STARR-seq mESC enhancer starr_13683 Neighboring gene STARR-positive B cell enhancer ABC_E1303 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:97425959-97426223 Neighboring gene predicted gene 9484 Neighboring gene BMP2 inducible kinase Neighboring gene STARR-positive B cell enhancer ABC_E3589 Neighboring gene STARR-seq mESC enhancer starr_13685 Neighboring gene STARR-seq mESC enhancer starr_13686 Neighboring gene STARR-positive B cell enhancer mm9_chr5:97540551-97540852 Neighboring gene predicted gene, 33609 Neighboring gene STARR-seq mESC enhancer starr_13687 Neighboring gene predicted gene 2861

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

General protein information

Preferred Names
progestin and adipoQ receptor family member 3
Names
Raf kinase trapping to Golgi

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359910.1NP_001346839.1  progestin and adipoQ receptor family member 3 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC125229, AK149213
    Consensus CDS
    CCDS19451.1
    UniProtKB/Swiss-Prot
    Q6TCG8
    UniProtKB/TrEMBL
    Q0VAZ2, Q3UEZ4
    Related
    ENSMUSP00000108593.4, ENSMUST00000112969.10
    Conserved Domains (1) summary
    pfam03006
    Location:64283
    HlyIII; Haemolysin-III related
  2. NM_001359913.1NP_001346842.1  progestin and adipoQ receptor family member 3 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC125229
    Consensus CDS
    CCDS89954.1
    UniProtKB/TrEMBL
    D3Z181
    Related
    ENSMUSP00000108592.2, ENSMUST00000112968.2
    Conserved Domains (1) summary
    cl03831
    Location:64170
    HlyIII; Haemolysin-III related
  3. NM_198422.3NP_940814.1  progestin and adipoQ receptor family member 3 isoform a

    See identical proteins and their annotated locations for NP_940814.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC125229
    Consensus CDS
    CCDS19451.1
    UniProtKB/Swiss-Prot
    Q6TCG8
    UniProtKB/TrEMBL
    Q0VAZ2, Q3UEZ4
    Related
    ENSMUSP00000069324.3, ENSMUST00000069453.9
    Conserved Domains (1) summary
    pfam03006
    Location:64283
    HlyIII; Haemolysin-III related

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    97229223..97259608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165068.1XP_036020961.1  progestin and adipoQ receptor family member 3 isoform X3

    Conserved Domains (1) summary
    cl03831
    Location:64217
    HlyIII; Haemolysin-III related
  2. XM_006534876.4XP_006534939.1  progestin and adipoQ receptor family member 3 isoform X2

    UniProtKB/TrEMBL
    Q3UEZ4
    Conserved Domains (1) summary
    cl03831
    Location:64262
    HlyIII; Haemolysin-III related
  3. XM_006534875.5XP_006534938.1  progestin and adipoQ receptor family member 3 isoform X1

    See identical proteins and their annotated locations for XP_006534938.1

    UniProtKB/Swiss-Prot
    Q6TCG8
    UniProtKB/TrEMBL
    Q0VAZ2, Q3UEZ4
    Conserved Domains (1) summary
    pfam03006
    Location:64283
    HlyIII; Haemolysin-III related
  4. XM_036165067.1XP_036020960.1  progestin and adipoQ receptor family member 3 isoform X2

    UniProtKB/TrEMBL
    Q3UEZ4
    Conserved Domains (1) summary
    cl03831
    Location:64262
    HlyIII; Haemolysin-III related