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Cwh43 cell wall biogenesis 43 C-terminal homolog [ Mus musculus (house mouse) ]

Gene ID: 231293, updated on 18-Apr-2024

Summary

Official Symbol
Cwh43provided by MGI
Official Full Name
cell wall biogenesis 43 C-terminal homologprovided by MGI
Primary source
MGI:MGI:2444131
See related
Ensembl:ENSMUSG00000029154 AllianceGenome:MGI:2444131
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
imds-60; C130090K23Rik
Summary
Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in head mesenchyme and otic capsule. Orthologous to human CWH43 (cell wall biogenesis 43 C-terminal homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in genital fat pad adult (RPKM 18.2), stomach adult (RPKM 13.1) and 6 other tissues See more
Orthologs
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Genomic context

Location:
5 C3.3; 5 38.78 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (73563394..73610778)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (73406051..73453435)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34583 Neighboring gene predicted gene, 35960 Neighboring gene STARR-seq mESC enhancer starr_13387 Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E153 Neighboring gene defective in cullin neddylation 1 domain containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (6)  1 citation
  • Gene trapped (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PGAP2-interacting protein
Names
cell wall biogenesis protein 43 C-terminal homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418155.1NP_001405084.1  PGAP2-interacting protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC108828, AC134551
    Related
    ENSMUSP00000069563.7, ENSMUST00000065543.8
  2. NM_181323.3NP_851840.1  PGAP2-interacting protein isoform 1

    See identical proteins and their annotated locations for NP_851840.1

    Status: VALIDATED

    Source sequence(s)
    AC108828, AC134551
    Consensus CDS
    CCDS19341.1
    UniProtKB/Swiss-Prot
    Q8CBQ1, Q91YL7
    Related
    ENSMUSP00000031040.7, ENSMUST00000031040.13
    Conserved Domains (1) summary
    pfam03372
    Location:451580
    Exo_endo_phos; Endonuclease/Exonuclease/phosphatase family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    73563394..73610778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320839.2XP_017176328.1  PGAP2-interacting protein isoform X1

    Conserved Domains (1) summary
    cl00490
    Location:443597
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
  2. XM_006503949.3XP_006504012.1  PGAP2-interacting protein isoform X2

    Conserved Domains (1) summary
    cl00490
    Location:354493
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
  3. XM_006503950.5XP_006504013.1  PGAP2-interacting protein isoform X3

RNA

  1. XR_003955627.2 RNA Sequence