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Strip1 striatin interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 229707, updated on 12-May-2024

Summary

Official Symbol
Strip1provided by MGI
Official Full Name
striatin interacting protein 1provided by MGI
Primary source
MGI:MGI:2443884
See related
Ensembl:ENSMUSG00000014601 AllianceGenome:MGI:2443884
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam40a; 6330569M22Rik; 6530401O14Rik
Summary
Enables protein kinase binding activity and small GTPase binding activity. Predicted to be involved in cortical actin cytoskeleton organization and regulation of cell morphogenesis. Predicted to be located in nucleus. Predicted to be active in cytosol. Is expressed in nervous system. Orthologous to human STRIP1 (striatin interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 58.8), CNS E14 (RPKM 55.3) and 28 other tissues See more
Orthologs
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Genomic context

See Strip1 in Genome Data Viewer
Location:
3 F2.3; 3 46.83 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (107519848..107539010, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (107612532..107631710, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36097 Neighboring gene ubiquitin-like 4B Neighboring gene aristaless-like homeobox 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:107434637-107434746 Neighboring gene predicted gene 10961 Neighboring gene S-adenosylhomocysteine hydrolase-like 1 Neighboring gene predicted gene, 52629

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC38111

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small GTPase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cortical actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cell morphogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
striatin-interacting protein 1
Names
family with sequence similarity 40, member A
protein FAM40A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153563.3NP_705791.2  striatin-interacting protein 1

    See identical proteins and their annotated locations for NP_705791.2

    Status: VALIDATED

    Source sequence(s)
    AC122902
    Consensus CDS
    CCDS51043.1
    UniProtKB/Swiss-Prot
    Q80T92, Q8BZC6, Q8C079, Q8CIF7
    UniProtKB/TrEMBL
    Q3UGC1
    Related
    ENSMUSP00000068587.6, ENSMUST00000064759.7
    Conserved Domains (2) summary
    pfam07923
    Location:66328
    N1221; N1221-like protein
    pfam11882
    Location:460783
    DUF3402; Domain of unknown function (DUF3402)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    107519848..107539010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)