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Samd10 sterile alpha motif domain containing 10 [ Mus musculus (house mouse) ]

Gene ID: 229011, updated on 26-Sep-2022

Summary

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Official Symbol
Samd10provided by MGI
Official Full Name
sterile alpha motif domain containing 10provided by MGI
Primary source
MGI:MGI:2443872
See related
Ensembl:ENSMUSG00000038605 AllianceGenome:MGI:2443872
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E130318E08; D930033N23Rik
Summary
Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasmic side of plasma membrane. Is expressed in nervous system and sensory organ. Orthologous to human SAMD10 (sterile alpha motif domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 37.9), CNS E18 (RPKM 29.7) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Samd10 in Genome Data Viewer
Location:
2; 2 H4
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181237008..181241227, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181595215..181599434, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene uridine-cytidine kinase 1-like 1 Neighboring gene uridine-cytidine kinase 1-like 1, opposite strand Neighboring gene zinc finger protein 512B Neighboring gene microRNA 7006 Neighboring gene pre-mRNA splicing factor 6 Neighboring gene predicted gene, 29797

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

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Preferred Names
sterile alpha motif domain-containing protein 10
Names
SAM domain-containing protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370751.1 → NP_001357680.1  sterile alpha motif domain-containing protein 10 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL844529
    Conserved Domains (1) summary
    cd09510
    Location:124 → 198
    SAM_aveugle-like; SAM domain of aveugle-like subfamily

  2. NM_172676.3 → NP_766264.2  sterile alpha motif domain-containing protein 10 isoform 1

    See identical proteins and their annotated locations for NP_766264.2

    Status: VALIDATED

    Source sequence(s)
    AL844529
    Consensus CDS
    CCDS17217.1
    UniProtKB/Swiss-Prot
    Q7TST3
    UniProtKB/TrEMBL
    Q3TBN2
    Related
    ENSMUSP00000060499.9, ENSMUST00000060173.9
    Conserved Domains (2) summary
    cd09510
    Location:113 → 187
    SAM_aveugle-like; SAM domain of aveugle-like subfamily
    smart00454
    Location:115 → 182
    SAM; Sterile alpha motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    181237008..181241227 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500607.4 → XP_006500670.1  sterile alpha motif domain-containing protein 10 isoform X1

    Conserved Domains (1) summary
    cd09510
    Location:85 → 159
    SAM_aveugle-like; SAM domain of aveugle-like subfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7TST3.1 GenPept UniProtKB/Swiss-Prot:Q7TST3

Gene LinkOut

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