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Slc39a10 solute carrier family 39 (zinc transporter), member 10 [ Mus musculus (house mouse) ]

Gene ID: 227059, updated on 24-Sep-2019

Summary

Official Symbol
Slc39a10provided by MGI
Official Full Name
solute carrier family 39 (zinc transporter), member 10provided by MGI
Primary source
MGI:MGI:1914515
See related
Ensembl:ENSMUSG00000025986
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zip10; mKIAA1265; 5430433I10; 2900042E17Rik
Expression
Broad expression in cortex adult (RPKM 17.1), frontal lobe adult (RPKM 14.5) and 22 other tissues See more
Orthologs

Genomic context

See Slc39a10 in Genome Data Viewer
Location:
1; 1 C1.1
Exon count:
15
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (46807544..46925776, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (46864389..46910354, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene heat shock protein 8 pseudogene Neighboring gene dynein, axonemal, heavy chain 7C Neighboring gene predicted gene, 39638 Neighboring gene DnaJ (Hsp40) homolog, subfamily B, member 6 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
metal ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
cellular zinc ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular zinc ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ion transport IEA
Inferred from Electronic Annotation
more info
 
metal ion transport IEA
Inferred from Electronic Annotation
more info
 
negative regulation of B cell apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of B cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of B cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of B cell receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein tyrosine phosphatase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
zinc ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion import across plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
zinc ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc transporter ZIP10
Names
ZIP-10
solute carrier family 39 member 10
zrt- and Irt-like protein 10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356416.1NP_001343345.1  zinc transporter ZIP10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC116452, AC124185
    Conserved Domains (1) summary
    pfam02535
    Location:406821
    Zip; ZIP Zinc transporter
  2. NM_001356417.1NP_001343346.1  zinc transporter ZIP10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC109276, AC116452, AC124185
    Conserved Domains (1) summary
    pfam02535
    Location:406821
    Zip; ZIP Zinc transporter
  3. NM_172653.3NP_766241.2  zinc transporter ZIP10 precursor

    See identical proteins and their annotated locations for NP_766241.2

    Status: VALIDATED

    Source sequence(s)
    AC116452, AC124185
    Consensus CDS
    CCDS14936.1
    UniProtKB/Swiss-Prot
    Q6P5F6
    Related
    ENSMUSP00000027131.4, ENSMUST00000027131.5
    Conserved Domains (1) summary
    pfam02535
    Location:406821
    Zip; ZIP Zinc transporter

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p6 C57BL/6J

    Range
    46807544..46925776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006495932.3XP_006495995.1  zinc transporter ZIP10 isoform X1

    Conserved Domains (1) summary
    pfam02535
    Location:416831
    Zip; ZIP Zinc transporter
  2. XM_006495933.4XP_006495996.1  zinc transporter ZIP10 isoform X2

    See identical proteins and their annotated locations for XP_006495996.1

    UniProtKB/Swiss-Prot
    Q6P5F6
    Conserved Domains (1) summary
    pfam02535
    Location:406821
    Zip; ZIP Zinc transporter
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