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Zfand5 zinc finger, AN1-type domain 5 [ Mus musculus (house mouse) ]

Gene ID: 22682, updated on 5-Mar-2024

Summary

Official Symbol
Zfand5provided by MGI
Official Full Name
zinc finger, AN1-type domain 5provided by MGI
Primary source
MGI:MGI:1278334
See related
Ensembl:ENSMUSG00000024750 AllianceGenome:MGI:1278334
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Za20d2; Zfp216; 2310057A04Rik; 5830475F03Rik
Summary
Predicted to enable DNA binding activity and zinc ion binding activity. Acts upstream of or within several processes, including face development; fibroblast migration; and platelet-derived growth factor receptor signaling pathway. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ZFAND5 (zinc finger AN1-type containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 34.4), ovary adult (RPKM 17.5) and 28 other tissues See more
Orthologs
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Genomic context

Location:
19 B; 19 14.32 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (21249150..21264204)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (21271786..21286840)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:21219297-21219406 Neighboring gene VISTA enhancer mm1562 Neighboring gene predicted gene, 32979 Neighboring gene STARR-seq mESC enhancer starr_45720 Neighboring gene predicted gene, 45918 Neighboring gene STARR-seq mESC enhancer starr_45722 Neighboring gene VISTA enhancer mm269 Neighboring gene predicted gene, 57661 Neighboring gene STARR-seq mESC enhancer starr_45723 Neighboring gene STARR-seq mESC enhancer starr_45724 Neighboring gene guanine deaminase Neighboring gene STARR-seq mESC enhancer starr_45725 Neighboring gene STARR-seq mESC enhancer starr_45726 Neighboring gene chromosome 19 C9orf57 homolog

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
AN1-type zinc finger protein 5
Names
zinc finger A20 domain-containing protein 2
zinc finger protein 216
zinc finger, A20 domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009551.5NP_033577.1  AN1-type zinc finger protein 5

    See identical proteins and their annotated locations for NP_033577.1

    Status: VALIDATED

    Source sequence(s)
    AC103947
    Consensus CDS
    CCDS29697.1
    UniProtKB/Swiss-Prot
    O88878, Q3B7K8
    Related
    ENSMUSP00000158187.2, ENSMUST00000237651.2
    Conserved Domains (2) summary
    smart00154
    Location:154191
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:1235
    zf-A20; A20-like zinc finger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    21249150..21264204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527058.4XP_006527121.1  AN1-type zinc finger protein 5 isoform X1

    See identical proteins and their annotated locations for XP_006527121.1

    UniProtKB/Swiss-Prot
    O88878, Q3B7K8
    Related
    ENSMUSP00000025659.5, ENSMUST00000025659.12
    Conserved Domains (2) summary
    smart00154
    Location:154191
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:1235
    zf-A20; A20-like zinc finger