Format

Send to:

Choose Destination

Slc7a4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 [ Mus musculus (house mouse) ]

Gene ID: 224022, updated on 14-Aug-2019

Summary

Official Symbol
Slc7a4provided by MGI
Official Full Name
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4provided by MGI
Primary source
MGI:MGI:2146512
See related
Ensembl:ENSMUSG00000022756
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI853530
Expression
Broad expression in genital fat pad adult (RPKM 44.4), ovary adult (RPKM 14.2) and 16 other tissues See more
Orthologs

Genomic context

See Slc7a4 in Genome Data Viewer
Location:
16; 16 A3
Exon count:
6
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (17572018..17576890, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (17572111..17576764, complement)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 74B Neighboring gene purinergic receptor P2X, ligand-gated ion channel, 6 Neighboring gene uncharacterized LOC115488657 Neighboring gene sphingomyelin phosphodiesterase 4 Neighboring gene coiled-coil domain containing 74A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Clone Names

  • MGC27672

Gene Ontology Provided by MGI

Function Evidence Code Pubs
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
amino acid transport IEA
Inferred from Electronic Annotation
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cationic amino acid transporter 4
Names
CAT-4
CAT4
solute carrier family 7 member 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359891.1NP_001346820.1  cationic amino acid transporter 4 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC115733
    Conserved Domains (1) summary
    cl26159
    Location:14592
    AA_permease_2; Amino acid permease
  2. NM_001359892.1NP_001346821.1  cationic amino acid transporter 4 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC115733
    Conserved Domains (1) summary
    cl26159
    Location:79657
    AA_permease_2; Amino acid permease
  3. NM_001359893.1NP_001346822.1  cationic amino acid transporter 4 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC115733
    Conserved Domains (1) summary
    cl26159
    Location:14592
    AA_permease_2; Amino acid permease
  4. NM_144852.3NP_659101.2  cationic amino acid transporter 4 isoform 2

    See identical proteins and their annotated locations for NP_659101.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK043772
    Consensus CDS
    CCDS28008.1
    UniProtKB/Swiss-Prot
    Q8BLQ7
    Related
    ENSMUSP00000127280.1, ENSMUST00000172164.9
    Conserved Domains (1) summary
    cl26159
    Location:14592
    AA_permease_2; Amino acid permease

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p6 C57BL/6J

    Range
    17572018..17576890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249071.1XP_030104931.1  cationic amino acid transporter 4 isoform X2

    Related
    ENSMUSP00000156027.1, ENSMUST00000231615.1
  2. XM_030249072.1XP_030104932.1  cationic amino acid transporter 4 isoform X2

    Related
    ENSMUSP00000156098.1, ENSMUST00000232385.1
  3. XM_017316950.2XP_017172439.1  cationic amino acid transporter 4 isoform X1

    UniProtKB/Swiss-Prot
    Q8BLQ7
    Conserved Domains (1) summary
    cl26159
    Location:14592
    AA_permease_2; Amino acid permease
  4. XM_030249070.1XP_030104930.1  cationic amino acid transporter 4 isoform X1

RNA

  1. XR_875780.3 RNA Sequence

  2. XR_875779.3 RNA Sequence

  3. XR_384551.4 RNA Sequence

  4. XR_384549.4 RNA Sequence

    Related
    ENSMUST00000232429.1
  5. XR_384548.4 RNA Sequence

  6. XR_875781.3 RNA Sequence

  7. XR_384553.4 RNA Sequence

Support Center