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Wbp1 WW domain binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 22377, updated on 26-Sep-2022

Summary

Official Symbol
Wbp1provided by MGI
Official Full Name
WW domain binding protein 1provided by MGI
Primary source
MGI:MGI:104710
See related
Ensembl:ENSMUSG00000030035 AllianceGenome:MGI:104710
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables WW domain binding activity. Orthologous to human WBP1 (WW domain binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 74.3), duodenum adult (RPKM 66.6) and 28 other tissues See more
Orthologs
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Genomic context

See Wbp1 in Genome Data Viewer
Location:
6; 6 C3
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83096025..83098442, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83119044..83121461, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 142 Neighboring gene mitochondrial ribosomal protein L53 Neighboring gene mannosyl-oligosaccharide glucosidase Neighboring gene INO80 complex subunit B Neighboring gene rhotekin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables WW domain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables WW domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables WW domain binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
WW domain-binding protein 1
Names
WBP-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083922.1NP_001077391.1  WW domain-binding protein 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).
    Source sequence(s)
    AI842692, AK076948, BY159385
    UniProtKB/TrEMBL
    Q8C5Y4
    Related
    ENSMUSP00000122900.2, ENSMUST00000146328.4
    Conserved Domains (1) summary
    pfam11669
    Location:70176
    WBP-1; WW domain-binding protein 1
  2. NM_001083923.1NP_001077392.1  WW domain-binding protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001077392.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 3), compared to isoform 1.
    Source sequence(s)
    AI842692, AK076948, BE860581, BY159385
    Consensus CDS
    CCDS39528.1
    UniProtKB/Swiss-Prot
    P97764
    UniProtKB/TrEMBL
    Q8C5Y4
    Related
    ENSMUSP00000109569.4, ENSMUST00000113936.10
    Conserved Domains (1) summary
    pfam11669
    Location:36142
    WBP-1; WW domain-binding protein 1
  3. NM_016757.2NP_058037.2  WW domain-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_058037.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AI842692, AK076948, BY159385, CX205200
    Consensus CDS
    CCDS39529.1
    UniProtKB/Swiss-Prot
    P97764, Q99J20
    UniProtKB/TrEMBL
    Q8C5Y4
    Related
    ENSMUSP00000032111.5, ENSMUST00000032111.11
    Conserved Domains (1) summary
    pfam11669
    Location:71177
    WBP-1; WW domain-binding protein 1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    83096025..83098442 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)