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RSPH10B radial spoke head 10 homolog B [ Homo sapiens (human) ]

Gene ID: 222967, updated on 6-Oct-2019

Summary

Official Symbol
RSPH10Bprovided by HGNC
Official Full Name
radial spoke head 10 homolog Bprovided by HGNC
Primary source
HGNC:HGNC:27362
See related
Ensembl:ENSG00000155026
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward testis (RPKM 16.5) See more
Orthologs

Genomic context

See RSPH10B in Genome Data Viewer
Location:
7p22.1
Exon count:
21
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (5926136..5970850, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (5965777..6010322, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene CCZ1 homolog, vacuolar protein trafficking and biogenesis associated Neighboring gene nonconserved acetylation island sequence 61 enhancer Neighboring gene uncharacterized LOC107986694 Neighboring gene PMS1 homolog 2, mismatch repair system component Neighboring gene aminoacyl tRNA synthetase complex interacting multifunctional protein 2 Neighboring gene small nucleolar RNA, H/ACA box 80D

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of radial spoke head 10 homolog B (RSPH10B) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC50833

General protein information

Preferred Names
radial spoke head 10 homolog B; radial spoke head 10 homolog B2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173565.3NP_775836.3  radial spoke head 10 homolog B

    Status: VALIDATED

    Source sequence(s)
    AC004983, AC005995, BC034495
    Consensus CDS
    CCDS34598.1
    UniProtKB/Swiss-Prot
    B2RC85
    Related
    ENSP00000384097.1, ENST00000404406.5
    Conserved Domains (4) summary
    smart00698
    Location:225244
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:104240
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:109129
    MORN; MORN repeat
    pfam13094
    Location:777853
    CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    5926136..5970850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011515204.2XP_011513506.1  radial spoke head 10 homolog B2 isoform X1

    See identical proteins and their annotated locations for XP_011513506.1

    Conserved Domains (1) summary
    cl27415
    Location:128318
    COG4642; Uncharacterized conserved protein [Function unknown]
  2. XM_011515209.3XP_011513511.1  radial spoke head 10 homolog B2 isoform X4

    Conserved Domains (4) summary
    smart00698
    Location:225244
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:104240
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:109129
    MORN; MORN repeat
    pfam13094
    Location:712788
    CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
  3. XM_005249659.4XP_005249716.1  radial spoke head 10 homolog B2 isoform X2

    See identical proteins and their annotated locations for XP_005249716.1

    UniProtKB/Swiss-Prot
    P0C881
    Conserved Domains (4) summary
    smart00698
    Location:225244
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:104240
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:109129
    MORN; MORN repeat
    pfam13094
    Location:777853
    CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
  4. XM_011515208.3XP_011513510.1  radial spoke head 10 homolog B2 isoform X3

    Conserved Domains (4) summary
    smart00698
    Location:225244
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:104240
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:109129
    MORN; MORN repeat
    pfam13094
    Location:717793
    CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
  5. XM_024446691.1XP_024302459.1  radial spoke head 10 homolog B2 isoform X1

    Conserved Domains (1) summary
    cl27415
    Location:128318
    COG4642; Uncharacterized conserved protein [Function unknown]
  6. XM_011515207.1XP_011513509.1  radial spoke head 10 homolog B2 isoform X1

    See identical proteins and their annotated locations for XP_011513509.1

    Conserved Domains (1) summary
    cl27415
    Location:128318
    COG4642; Uncharacterized conserved protein [Function unknown]
  7. XM_011515203.1XP_011513505.1  radial spoke head 10 homolog B2 isoform X1

    See identical proteins and their annotated locations for XP_011513505.1

    Conserved Domains (1) summary
    cl27415
    Location:128318
    COG4642; Uncharacterized conserved protein [Function unknown]
  8. XM_011515211.1XP_011513513.1  radial spoke head 10 homolog B2 isoform X7

  9. XM_011515210.1XP_011513512.1  radial spoke head 10 homolog B2 isoform X6

    Conserved Domains (2) summary
    smart00698
    Location:1231
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    pfam02493
    Location:7193
    MORN; MORN repeat
  10. XM_017011870.2XP_016867359.1  radial spoke head 10 homolog B2 isoform X5

  11. XM_011515212.3XP_011513514.1  radial spoke head 10 homolog B2 isoform X8

    Conserved Domains (3) summary
    smart00698
    Location:225244
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:104240
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:109129
    MORN; MORN repeat
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