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Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 [ Mus musculus (house mouse) ]

Gene ID: 22273, updated on 7-Apr-2019

Summary

Official Symbol
Uqcrc1provided by MGI
Official Full Name
ubiquinol-cytochrome c reductase core protein 1provided by MGI
Primary source
MGI:MGI:107876
See related
Ensembl:ENSMUSG00000025651
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110032G10Rik
Expression
Ubiquitous expression in heart adult (RPKM 872.4), duodenum adult (RPKM 565.1) and 28 other tissues See more
Orthologs

Genomic context

See Uqcrc1 in Genome Data Viewer
Location:
9 F2; 9 59.63 cM
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (108936648..108949641)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (108838661..108851686)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 26, member 6 Neighboring gene transmembrane protein 89 Neighboring gene collagen, type VII, alpha 1 Neighboring gene microRNA 711 Neighboring gene urocortin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC97899

Gene Ontology Provided by MGI

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
mitochondrial electron transport, ubiquinol to cytochrome c IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial electron transport, ubiquinol to cytochrome c IDA
Inferred from Direct Assay
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane HDA PubMed 
mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial respiratory chain complex III ISO
Inferred from Sequence Orthology
more info
 
mitochondrion HDA PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
myelin sheath HDA PubMed 
respiratory chain IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cytochrome b-c1 complex subunit 1, mitochondrial
Names
complex III subunit 1
core protein I
ubiquinol-cytochrome-c reductase complex core protein 1
NP_079683.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025407.2NP_079683.2  cytochrome b-c1 complex subunit 1, mitochondrial precursor

    See identical proteins and their annotated locations for NP_079683.2

    Status: VALIDATED

    Source sequence(s)
    AI462428, AK010553, BB649589, BY260300
    Consensus CDS
    CCDS23540.1
    UniProtKB/Swiss-Prot
    Q9CZ13
    Related
    ENSMUSP00000026743.8, ENSMUST00000026743.13
    Conserved Domains (3) summary
    COG0612
    Location:46469
    PqqL; Predicted Zn-dependent peptidase [General function prediction only]
    pfam00675
    Location:58205
    Peptidase_M16; Insulinase (Peptidase family M16)
    pfam05193
    Location:210395
    Peptidase_M16_C; Peptidase M16 inactive domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    108936648..108949641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 PATCHES

Genomic

  1. NW_012132906.1 Reference GRCm38.p4 PATCHES

    Range
    103563..116556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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