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PXDC1 PX domain containing 1 [ Homo sapiens (human) ]

Gene ID: 221749, updated on 5-Aug-2022

Summary

Official Symbol
PXDC1provided by HGNC
Official Full Name
PX domain containing 1provided by HGNC
Primary source
HGNC:HGNC:21361
See related
Ensembl:ENSG00000168994 AllianceGenome:HGNC:21361
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf145
Summary
Predicted to enable phosphatidylinositol binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver (RPKM 40.1), placenta (RPKM 24.5) and 24 other tissues See more
Orthologs
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Genomic context

See PXDC1 in Genome Data Viewer
Location:
6p25.2
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (3722619..3751713, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (3591565..3620651, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (3722853..3751947, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100507336 Neighboring gene uncharacterized LOC124901243 Neighboring gene translocase of outer mitochondrial membrane 5 homolog (yeast) pseudogene Neighboring gene Sharpr-MPRA regulatory region 15708 Neighboring gene Sharpr-MPRA regulatory region 8997 Neighboring gene uncharacterized LOC124901244

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PX domain-containing protein 1
Names
PX domain-containing protein C6orf145

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183373.4NP_899229.2  PX domain-containing protein 1

    See identical proteins and their annotated locations for NP_899229.2

    Status: VALIDATED

    Source sequence(s)
    AK024828, AK289598, BC056908, DA164068
    Consensus CDS
    CCDS4486.1
    UniProtKB/Swiss-Prot
    Q5TGL8, Q86XB7
    Related
    ENSP00000369636.5, ENST00000380283.5
    Conserved Domains (1) summary
    cl02563
    Location:46127
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    3722619..3751713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011514393.4XP_011512695.1  PX domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    cl02563
    Location:3567
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  2. XM_047418376.1XP_047274332.1  PX domain-containing protein 1 isoform X1

    Related
    ENSP00000369630.2, ENST00000380277.6

RNA

  1. XR_007059222.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    3591565..3620651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)