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Rpl13a ribosomal protein L13A [ Mus musculus (house mouse) ]

Gene ID: 22121, updated on 8-Jan-2023

Summary

Official Symbol
Rpl13aprovided by MGI
Official Full Name
ribosomal protein L13Aprovided by MGI
Primary source
MGI:MGI:1351455
See related
Ensembl:ENSMUSG00000074129 AllianceGenome:MGI:1351455
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tstap198-7; tum-antigen; 1810026N22Rik
Summary
Enables mRNA binding activity. Involved in cellular response to interferon-gamma and negative regulation of translation. Acts upstream of or within several processes, including lung morphogenesis; macrophage chemotaxis; and response to lipopolysaccharide. Part of GAIT complex and ribonucleoprotein complex. Orthologous to human RPL13A (ribosomal protein L13a). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 459.7), bladder adult (RPKM 448.2) and 28 other tissues See more
Orthologs
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Genomic context

See Rpl13a in Genome Data Viewer
Location:
7 B3; 7 29.14 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44774987..44778169, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45125563..45128745, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 45552 Neighboring gene microRNA 150 Neighboring gene small nucleolar RNA, C/D box 35B Neighboring gene ribosomal protein S11 Neighboring gene small nucleolar RNA, C/D box 35A Neighboring gene small nucleolar RNA, C/D box 34 Neighboring gene small nucleolar RNA, C/D box 32A Neighboring gene small nucleolar RNA, C/D box 33 Neighboring gene microRNA 5121 Neighboring gene FMS-like tyrosine kinase 3 ligand Neighboring gene aldehyde dehydrogenase 16 family, member A1 Neighboring gene PIH1 domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC107571

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular response to type II interferon IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to type II interferon ISO
Inferred from Sequence Orthology
more info
 
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within homeostatic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lung morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within macrophage chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of formation of translation preinitiation complex ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of translation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of translation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to lipopolysaccharide IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
PubMed 
part_of ribonucleoprotein complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in ribosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
60S ribosomal protein L13a
Names
tissue specific transplantation antigen P198-7
transplantation antigen P198
tum-P198 antigen
tum-transplantation antigen P198

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009438.5NP_033464.2  60S ribosomal protein L13a

    See identical proteins and their annotated locations for NP_033464.2

    Status: VALIDATED

    Source sequence(s)
    AV445288, BC042392, BC086896
    Consensus CDS
    CCDS21230.1
    UniProtKB/Swiss-Prot
    P19253
    UniProtKB/TrEMBL
    A0A8C6HLX2, Q5M9M0
    Related
    ENSMUSP00000115722.2, ENSMUST00000150350.9
    Conserved Domains (1) summary
    PTZ00068
    Location:6191
    PTZ00068; 60S ribosomal protein L13a; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    44774987..44778169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)