Format

Send to:

Choose Destination

Hsp90b1 heat shock protein 90, beta (Grp94), member 1 [ Mus musculus (house mouse) ]

Gene ID: 22027, updated on 18-Apr-2019

Summary

Official Symbol
Hsp90b1provided by MGI
Official Full Name
heat shock protein 90, beta (Grp94), member 1provided by MGI
Primary source
MGI:MGI:98817
See related
Ensembl:ENSMUSG00000020048
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TA-3; Tra1; gp96; ERp99; GRP94; Targ2; Tra-1; endoplasmin
Expression
Broad expression in placenta adult (RPKM 303.0), CNS E11.5 (RPKM 168.9) and 20 other tissues See more
Orthologs

Genomic context

See Hsp90b1 in Genome Data Viewer
Location:
10 C1; 10 43.05 cM
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (86690841..86705444, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (86153586..86168189, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene 5174 Neighboring gene RIKEN cDNA 1810014B01 gene Neighboring gene tetratricopeptide repeat domain 41 Neighboring gene fatty acid binding protein 3, muscle and heart, pseudogene 1 Neighboring gene 5'-nucleotidase domain containing 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding ISO
Inferred from Sequence Orthology
more info
 
low-density lipoprotein particle receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
actin rod assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to ATP ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of phosphoprotein phosphatase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
retrograde protein transport, ER to cytosol ISO
Inferred from Sequence Orthology
more info
 
ubiquitin-dependent ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ubiquitin-dependent ERAD pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum chaperone complex IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum lumen ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
midbody ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
smooth endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
endoplasmin
Names
94 kDa glucose-regulated protein
endoplasmic reticulum resident protein 99
heat shock protein 90 kDa beta member 1
polymorphic tumor rejection antigen 1
transforming growth factor alpha regulated gene 2
tumor rejection antigen (gp96) 1
tumor rejection antigen gp96

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011631.1NP_035761.1  endoplasmin precursor

    See identical proteins and their annotated locations for NP_035761.1

    Status: PROVISIONAL

    Source sequence(s)
    J03297
    Consensus CDS
    CCDS36019.1
    UniProtKB/Swiss-Prot
    P08113
    UniProtKB/TrEMBL
    Q3UAD6
    Related
    ENSMUSP00000020238.7, ENSMUST00000020238.13
    Conserved Domains (3) summary
    smart00387
    Location:96254
    HATPase_c; Histidine kinase-like ATPases
    PRK05218
    Location:74746
    PRK05218; heat shock protein 90; Provisional
    pfam00183
    Location:257783
    HSP90; Hsp90 protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

    Range
    86690841..86705444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center