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Inmt indolethylamine N-methyltransferase [ Mus musculus (house mouse) ]

Gene ID: 21743, updated on 19-Feb-2019

Summary

Official Symbol
Inmtprovided by MGI
Official Full Name
indolethylamine N-methyltransferaseprovided by MGI
Primary source
MGI:MGI:102963
See related
Ensembl:ENSMUSG00000003477
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Temt
Expression
Biased expression in lung adult (RPKM 556.8), liver adult (RPKM 128.3) and 1 other tissue See more
Orthologs

Genomic context

See Inmt in Genome Data Viewer
Location:
6; 6 B3
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (55170627..55174990, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (55120621..55124984, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene corticotropin releasing hormone receptor 2 Neighboring gene predicted gene, 34358 Neighboring gene MINDY lysine 48 deubiquitinase 4 Neighboring gene predicted gene, 38819

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
amine N-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
thioether S-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
thioether S-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
amine metabolic process ISO
Inferred from Sequence Orthology
more info
 
methylation ISO
Inferred from Sequence Orthology
more info
 
response to toxic substance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
indolethylamine N-methyltransferase
Names
amine N-methyltransferase
aromatic alkylamine N-methyltransferase
arylamine N-methyltransferase
indolamine N-methyltransferase
nicotine N-methyltransferase
thioether S-methyltransferase
NP_033375.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009349.3NP_033375.1  indolethylamine N-methyltransferase

    See identical proteins and their annotated locations for NP_033375.1

    Status: PROVISIONAL

    Source sequence(s)
    AC079243
    Consensus CDS
    CCDS20163.1
    UniProtKB/Swiss-Prot
    P40936
    Related
    ENSMUSP00000003569.5, ENSMUST00000003569.5
    Conserved Domains (1) summary
    pfam01234
    Location:1260
    NNMT_PNMT_TEMT; NNMT/PNMT/TEMT family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    55170627..55174990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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