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Zfp609 zinc finger protein 609 [ Mus musculus (house mouse) ]

Gene ID: 214812, updated on 2-Nov-2024

Summary

Official Symbol
Zfp609provided by MGI
Official Full Name
zinc finger protein 609provided by MGI
Primary source
MGI:MGI:2674092
See related
Ensembl:ENSMUSG00000040524 AllianceGenome:MGI:2674092
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf609; mKIAA0295; 9830165N24
Summary
Enables promoter-specific chromatin binding activity. Involved in positive regulation of neuron migration; positive regulation of transcription by RNA polymerase II; and regulation of myoblast proliferation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brown fat; early conceptus; genitourinary system; gut; and nervous system. Orthologous to human ZNF609 (zinc finger protein 609). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 8.8), CNS E14 (RPKM 8.3) and 28 other tissues See more
Orthologs
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Genomic context

See Zfp609 in Genome Data Viewer
Location:
9 C; 9 35.46 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (65598860..65735004, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (65691578..65827564, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_24467 Neighboring gene RNA binding protein with multiple splicing 2 Neighboring gene STARR-positive B cell enhancer ABC_E9768 Neighboring gene STARR-seq mESC enhancer starr_24469 Neighboring gene ornithine decarboxylase antizyme 2 Neighboring gene STARR-seq mESC enhancer starr_24471 Neighboring gene ATP synthase subunit f, mitochondrial-like Neighboring gene thyroid hormone receptor interactor 4 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 53535

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables promoter-specific chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172536.3NP_766124.2  zinc finger protein 609

    See identical proteins and their annotated locations for NP_766124.2

    Status: VALIDATED

    Source sequence(s)
    AC121979, AK036715, BC016271, BC058943, BF465900
    Consensus CDS
    CCDS23297.2
    UniProtKB/Swiss-Prot
    Q05DD7, Q6PD47, Q6ZQE3, Q8BZ47
    UniProtKB/TrEMBL
    B2RWS7
    Related
    ENSMUSP00000124089.2, ENSMUST00000159109.2
    Conserved Domains (2) summary
    PTZ00449
    Location:10051228
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    COG5189
    Location:412533
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    65598860..65735004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154823.1XP_036010716.1  zinc finger protein 609 isoform X3

    UniProtKB/TrEMBL
    B2RWS7
    Conserved Domains (1) summary
    COG5189
    Location:163284
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
  2. XM_006511007.5XP_006511070.1  zinc finger protein 609 isoform X2

    UniProtKB/TrEMBL
    B2RWS7
    Conserved Domains (2) summary
    PTZ00449
    Location:776999
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    COG5189
    Location:183304
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
  3. XM_036154822.1XP_036010715.1  zinc finger protein 609 isoform X1

    UniProtKB/TrEMBL
    B2RWS7
    Conserved Domains (2) summary
    PTZ00449
    Location:10051228
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    COG5189
    Location:412533
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]