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Tbp TATA box binding protein [ Mus musculus (house mouse) ]

Gene ID: 21374, updated on 8-Jul-2018
Official Symbol
Tbpprovided by MGI
Official Full Name
TATA box binding proteinprovided by MGI
Primary source
MGI:MGI:101838
See related
Ensembl:ENSMUSG00000014767 Vega:OTTMUSG00000030550
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gtf2d; SCA17; TFIID; GTF2D1
Expression
Ubiquitous expression in testis adult (RPKM 40.6), CNS E14 (RPKM 17.0) and 27 other tissues See more
Orthologs
See Tbp in Genome Data Viewer
Location:
17 A2; 17 8.95 cM
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (15499888..15517427)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (15636852..15654391)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 120, member B Neighboring gene proteasome (prosome, macropain) subunit, beta type 1 Neighboring gene programmed cell death 2 Neighboring gene zinc finger protein 91 pseudogene

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II core promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II repressing transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase III regulatory region DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
TFIIB-class transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
aryl hydrocarbon receptor binding ISO
Inferred from Sequence Orthology
more info
 
core promoter binding ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
repressing transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
DNA-templated transcription, initiation IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II transcriptional preinitiation complex assembly ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase III transcriptional preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
transcription by RNA polymerase III IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription by RNA polymerase III ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
RNA polymerase I transcription factor complex TAS
Traceable Author Statement
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
female pronucleus IDA
Inferred from Direct Assay
more info
PubMed 
male pronucleus IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromatin ISO
Inferred from Sequence Orthology
more info
 
nuclear euchromatin ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
pronucleus IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
transcription factor TFIIA complex ISO
Inferred from Sequence Orthology
more info
 
transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor TFIID complex ISO
Inferred from Sequence Orthology
more info
PubMed 
transcription factor TFIIIB complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcriptional preinitiation complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
TATA-box-binding protein
Names
TATA sequence-binding protein
TATA-binding factor
TATA-binding protein
TATA-box factor
TFIID core protein
transcription initiation factor TFIID TBP subunit

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013684.3NP_038712.3  TATA-box-binding protein

    See identical proteins and their annotated locations for NP_038712.3

    Status: VALIDATED

    Source sequence(s)
    AC154378, AK085037
    Consensus CDS
    CCDS37454.2
    UniProtKB/Swiss-Prot
    P29037
    UniProtKB/TrEMBL
    Q6RI65
    Related
    ENSMUSP00000124317.1, OTTMUSP00000039699, ENSMUST00000162505.7, OTTMUST00000075644
    Conserved Domains (2) summary
    PLN00062
    Location:139315
    PLN00062; TATA-box-binding protein; Provisional
    cd04516
    Location:139312
    TBP_eukaryotes; eukaryotic TATA box binding protein (TBP): Present in archaea and eukaryotes, TBPs are transcription factors that recognize promoters and initiate transcription. TBP has been shown to be an essential component of three different transcription initiation ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    15499888..15517427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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