U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Sh3bgrl2 SH3 domain binding glutamic acid-rich protein like 2 [ Mus musculus (house mouse) ]

Gene ID: 212531, updated on 5-Mar-2024

Summary

Official Symbol
Sh3bgrl2provided by MGI
Official Full Name
SH3 domain binding glutamic acid-rich protein like 2provided by MGI
Primary source
MGI:MGI:1915350
See related
Ensembl:ENSMUSG00000032261 AllianceGenome:MGI:1915350
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B930089I21; A930014C21Rik
Summary
Predicted to enable SH3 domain binding activity. Predicted to be located in nuclear membrane and nucleoplasm. Is expressed in brain. Orthologous to human SH3BGRL2 (SH3 domain binding glutamate rich protein like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in colon adult (RPKM 3.6), bladder adult (RPKM 2.8) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Sh3bgrl2 in Genome Data Viewer
Location:
9 E2; 9 45.49 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (83430391..83482345)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (83548338..83600292)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene Leber congenital amaurosis 5 (human) Neighboring gene STARR-positive B cell enhancer mm9_chr9:83334629-83334930 Neighboring gene predicted gene 2087 Neighboring gene STARR-seq mESC enhancer starr_24788 Neighboring gene ribosomal protein S15A, pseudogene Neighboring gene STARR-seq mESC enhancer starr_24789 Neighboring gene STARR-seq mESC enhancer starr_24791 Neighboring gene predicted gene, 39384 Neighboring gene STARR-positive B cell enhancer mm9_chr9:83503556-83503857 Neighboring gene STARR-seq mESC enhancer starr_24792 Neighboring gene predicted gene, 36120 Neighboring gene predicted gene 2109

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SH3 domain-binding glutamic acid-rich-like protein 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172507.5NP_766095.1  SH3 domain-binding glutamic acid-rich-like protein 2

    See identical proteins and their annotated locations for NP_766095.1

    Status: PROVISIONAL

    Source sequence(s)
    AC113158, AC125106
    Consensus CDS
    CCDS40708.1
    UniProtKB/Swiss-Prot
    Q3TV64, Q8BG73
    UniProtKB/TrEMBL
    A0A087WS96, Q8C073
    Related
    ENSMUSP00000108841.4, ENSMUST00000113215.10
    Conserved Domains (1) summary
    cd03030
    Location:297
    GRX_SH3BGR; Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif. ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    83430391..83482345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)