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Wdr25 WD repeat domain 25 [ Mus musculus (house mouse) ]

Gene ID: 212198, updated on 5-Mar-2024

Summary

Official Symbol
Wdr25provided by MGI
Official Full Name
WD repeat domain 25provided by MGI
Primary source
MGI:MGI:3045255
See related
Ensembl:ENSMUSG00000040877 AllianceGenome:MGI:3045255
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B930090D16Rik
Summary
Orthologous to human WDR25 (WD repeat domain 25). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in genital fat pad adult (RPKM 3.5), testis adult (RPKM 1.8) and 28 other tissues See more
Orthologs
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Genomic context

Location:
12 F1; 12 59.7 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (108860155..108994380)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (108894152..109028454)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 47 Neighboring gene predicted gene, 22079 Neighboring gene tryptophanyl-tRNA synthetase1 Neighboring gene STARR-positive B cell enhancer ABC_E5353 Neighboring gene STARR-seq mESC enhancer starr_33252 Neighboring gene STARR-seq mESC enhancer starr_33253 Neighboring gene STARR-seq mESC enhancer starr_33254 Neighboring gene peptidyl prolyl isomerase H pseudogene Neighboring gene STARR-seq mESC enhancer starr_33255 Neighboring gene brain-enriched guanylate kinase-associated Neighboring gene predicted gene, 52002 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:110295982-110296239 Neighboring gene STARR-positive B cell enhancer mm9_chr12:110312387-110312688 Neighboring gene STARR-positive B cell enhancer mm9_chr12:110313106-110313407 Neighboring gene macrophage migration inhibitory factor, pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
WD repeat-containing protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177602.3NP_808270.2  WD repeat-containing protein 25

    See identical proteins and their annotated locations for NP_808270.2

    Status: VALIDATED

    Source sequence(s)
    AC122811, AC140111
    Consensus CDS
    CCDS49172.1
    UniProtKB/Swiss-Prot
    E9Q349, Q8C4T7
    Related
    ENSMUSP00000129855.2, ENSMUST00000167816.8
    Conserved Domains (2) summary
    cd00200
    Location:230534
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:242281
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    108860155..108994380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515661.4XP_006515724.1  WD repeat-containing protein 25 isoform X2

    Conserved Domains (2) summary
    sd00039
    Location:240280
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:230358
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_011244056.4XP_011242358.1  WD repeat-containing protein 25 isoform X4

    Conserved Domains (2) summary
    sd00039
    Location:240280
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:230360
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_006515660.5XP_006515723.1  WD repeat-containing protein 25 isoform X1

    See identical proteins and their annotated locations for XP_006515723.1

    UniProtKB/Swiss-Prot
    E9Q349, Q8C4T7
    Conserved Domains (2) summary
    cd00200
    Location:230534
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:242281
    7WD40; WD40 repeat [structural motif]
  4. XM_011244054.4XP_011242356.1  WD repeat-containing protein 25 isoform X1

    See identical proteins and their annotated locations for XP_011242356.1

    UniProtKB/Swiss-Prot
    E9Q349, Q8C4T7
    Conserved Domains (2) summary
    cd00200
    Location:230534
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:242281
    7WD40; WD40 repeat [structural motif]
  5. XM_006515657.4XP_006515720.1  WD repeat-containing protein 25 isoform X1

    See identical proteins and their annotated locations for XP_006515720.1

    UniProtKB/Swiss-Prot
    E9Q349, Q8C4T7
    Conserved Domains (2) summary
    cd00200
    Location:230534
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:242281
    7WD40; WD40 repeat [structural motif]
  6. XM_006515662.4XP_006515725.1  WD repeat-containing protein 25 isoform X3

    Conserved Domains (2) summary
    sd00039
    Location:241282
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:228441
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  7. XM_011244057.4XP_011242359.1  WD repeat-containing protein 25 isoform X5

    Conserved Domains (2) summary
    sd00039
    Location:240280
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:230349
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  8. XM_011244055.3XP_011242357.1  WD repeat-containing protein 25 isoform X1

    See identical proteins and their annotated locations for XP_011242357.1

    UniProtKB/Swiss-Prot
    E9Q349, Q8C4T7
    Related
    ENSMUSP00000035553.8, ENSMUST00000047115.9
    Conserved Domains (2) summary
    cd00200
    Location:230534
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:242281
    7WD40; WD40 repeat [structural motif]
  9. XM_006515658.4XP_006515721.1  WD repeat-containing protein 25 isoform X1

    See identical proteins and their annotated locations for XP_006515721.1

    UniProtKB/Swiss-Prot
    E9Q349, Q8C4T7
    Conserved Domains (2) summary
    cd00200
    Location:230534
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:242281
    7WD40; WD40 repeat [structural motif]

RNA

  1. XR_003950025.2 RNA Sequence