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Metrnl meteorin, glial cell differentiation regulator-like [ Mus musculus (house mouse) ]

Gene ID: 210029, updated on 12-May-2024

Summary

Official Symbol
Metrnlprovided by MGI
Official Full Name
meteorin, glial cell differentiation regulator-likeprovided by MGI
Primary source
MGI:MGI:2384806
See related
Ensembl:ENSMUSG00000039208 AllianceGenome:MGI:2384806
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9430048M07Rik
Summary
Enables hormone activity. Involved in several processes, including brown fat cell differentiation; energy homeostasis; and positive regulation of brown fat cell differentiation. Located in extracellular space. Is expressed in central nervous system; sensory organ; skeleton; and vibrissa. Orthologous to human METRNL (meteorin like, glial cell differentiation regulator). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 47.4), duodenum adult (RPKM 44.8) and 16 other tissues See more
Orthologs
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Genomic context

See Metrnl in Genome Data Viewer
Location:
11 E2; 11 86.89 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (121593253..121608215)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (121702427..121717389)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 Neighboring gene predicted gene, 53659 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:121534171-121534280 Neighboring gene STARR-positive B cell enhancer mm9_chr11:121534352-121534653 Neighboring gene ribosomal protein, large, P0 pseudogene Neighboring gene predicted gene 12589 Neighboring gene predicted gene, 30338 Neighboring gene STARR-seq mESC enhancer starr_31386 Neighboring gene patched domain containing 3 Neighboring gene predicted gene, 57581

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 
  • Targeted (7)  1 citation

General gene information

Clone Names

  • MGC25696

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hormone activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables hormone activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space HDA PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
meteorin-like protein
Names
cometin
subfatin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144797.3NP_659046.1  meteorin-like protein precursor

    See identical proteins and their annotated locations for NP_659046.1

    Status: PROVISIONAL

    Source sequence(s)
    AK034855
    Consensus CDS
    CCDS25781.1
    UniProtKB/Swiss-Prot
    Q8R1J2, Q8VE43
    Related
    ENSMUSP00000038126.8, ENSMUST00000036742.14

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    121593253..121608215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)