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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_009442.1 RefSeqGene
- Range
-
4979..89622
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_465
mRNA and Protein(s)
-
NM_000124.4 → NP_000115.1 DNA excision repair protein ERCC-6 isoform 2
See identical proteins and their annotated locations for NP_000115.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) represents the longest transcript and encodes the longer protein (isoform 2).
- Source sequence(s)
-
AB209504, AC073366, AL138760, DA457690, L04791
- Consensus CDS
-
CCDS7229.1
- UniProtKB/Swiss-Prot
-
Q03468
- UniProtKB/TrEMBL
-
Q59FF6
- Related
- ENSP00000348089.5, ENST00000355832.10
- Conserved Domains (3) summary
-
- cd00046
Location:527 → 677
- DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
- cd00079
Location:830 → 960
- HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
- pfam00176
Location:510 → 812
- SNF2_N; SNF2 family N-terminal domain
-
NM_001277058.2 → NP_001263987.1 ERCC6-PGBD3 fusion protein isoform 1
See identical proteins and their annotated locations for NP_001263987.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) contains an alternate 3' terminal exon, compared to variant 3. It is generated as a result of splicing of ERCC6 exon 5 to the 3' splice site upstream of the PGBD3 ORF that activates the alternative polyadenylation site downstream of the PGBD3 ORF. The resulting protein (isoform 1, ERCC6-PGBD3 fusion protein) is shorter and has a distinct C-terminus, compared to isoform 2.
- Source sequence(s)
-
AC073366, AK291018, AL138760
- Consensus CDS
-
CCDS60529.1
- UniProtKB/Swiss-Prot
-
P0DP91
- UniProtKB/TrEMBL
-
A8K4Q3
- Related
- ENSP00000387966.2, ENST00000447839.6
- Conserved Domains (1) summary
-
- pfam13843
Location:609 → 967
- DDE_Tnp_1_7; Transposase IS4
-
NM_001277059.2 → NP_001263988.1 ERCC6-PGBD3 fusion protein isoform 1
See identical proteins and their annotated locations for NP_001263988.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and contains an alternate 3' terminal exon, compared to variant 3. It is generated as a result of splicing of ERCC6 exon 5 to the 3' splice site upstream of the PGBD3 ORF that activates the alternative polyadenylation site downstream of the PGBD3 ORF. The resulting protein (isoform 1, ERCC6-PGBD3 fusion protein) is shorter and has a distinct C-terminus, compared to isoform 2.
- Source sequence(s)
-
AK291018, AL138760, BC034479
- Consensus CDS
-
CCDS60529.1
- UniProtKB/Swiss-Prot
-
P0DP91
- UniProtKB/TrEMBL
-
A8K4Q3
- Related
- ENSP00000423550.1, ENST00000515869.1
- Conserved Domains (1) summary
-
- pfam13843
Location:609 → 967
- DDE_Tnp_1_7; Transposase IS4
-
NM_001346440.2 → NP_001333369.1 DNA excision repair protein ERCC-6 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (4 ) uses an alternate splice site in the 5' UTR, compared to variant 3, and encodes isoform 2. Variants 3 and 4 encode the same protein (isoform 2).
- Source sequence(s)
-
AC073366, AL138760, DA457690, L04791
- Consensus CDS
-
CCDS7229.1
- UniProtKB/Swiss-Prot
-
Q03468
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p13 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p13 Primary Assembly
- Range
-
49434881..49539538 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)