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Sox5 SRY (sex determining region Y)-box 5 [ Mus musculus (house mouse) ]

Gene ID: 20678, updated on 12-May-2024

Summary

Official Symbol
Sox5provided by MGI
Official Full Name
SRY (sex determining region Y)-box 5provided by MGI
Primary source
MGI:MGI:98367
See related
Ensembl:ENSMUSG00000041540 AllianceGenome:MGI:98367
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A730017D01Rik
Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cartilage condensation; chondrocyte differentiation; and positive regulation of chondrocyte differentiation. Acts upstream of or within several processes, including neurogenesis; regulation of timing of neuron differentiation; and regulation of transcription, DNA-templated. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SOX5 (SRY-box transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in whole brain E14.5 (RPKM 6.6), testis adult (RPKM 6.4) and 17 other tissues See more
Orthologs
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Genomic context

See Sox5 in Genome Data Viewer
Location:
6 G3; 6 76.14 cM
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (143774151..144728008, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (143828425..144782287, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31521 Neighboring gene STARR-seq mESC enhancer starr_17745 Neighboring gene predicted gene, 46720 Neighboring gene STARR-seq mESC enhancer starr_17746 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:143816722-143816875 Neighboring gene STARR-seq mESC enhancer starr_17747 Neighboring gene predicted gene, 32010 Neighboring gene predicted gene, 52486 Neighboring gene predicted gene, 52485 Neighboring gene STARR-seq mESC enhancer starr_17748 Neighboring gene STARR-seq mESC enhancer starr_17751 Neighboring gene predicted gene, 38531 Neighboring gene STARR-seq mESC enhancer starr_17756 Neighboring gene STARR-seq mESC enhancer starr_17757 Neighboring gene STARR-seq mESC enhancer starr_17758 Neighboring gene STARR-positive B cell enhancer ABC_E10417 Neighboring gene STARR-positive B cell enhancer mm9_chr6:144637695-144637995 Neighboring gene STARR-seq mESC enhancer starr_17759 Neighboring gene SRY (sex determining region Y)-box 5, opposite strand 3 Neighboring gene STARR-positive B cell enhancer mm9_chr6:144788652-144788953 Neighboring gene SRY (sex determining region Y)-box 5, opposite strand 4 Neighboring gene STARR-seq mESC enhancer starr_17760 Neighboring gene predicted gene, 32124 Neighboring gene predicted gene, 22792 Neighboring gene predicted gene, 20124

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC124352

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in asymmetric neuroblast division ISO
Inferred from Sequence Orthology
more info
 
involved_in cartilage condensation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cartilage development IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within cartilage development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cartilage development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in cell fate commitment IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell fate commitment IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cellular response to transforming growth factor beta stimulus ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within central nervous system neuron differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in chondrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within oligodendrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cartilage development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of chondrocyte differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of chondrocyte differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of chondrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of mesenchymal stem cell differentiation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of timing of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transcription regulator complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transcription factor SOX-5
Names
SRY-box containing gene 5

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113559.2NP_001107031.2  transcription factor SOX-5 isoform b

    See identical proteins and their annotated locations for NP_001107031.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.
    Source sequence(s)
    AC161059, AC167021, BC110478
    Consensus CDS
    CCDS51954.2
    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    UniProtKB/TrEMBL
    Q2TBA9
    Related
    ENSMUSP00000076403.6, ENSMUST00000077160.12
    Conserved Domains (1) summary
    cd01388
    Location:507578
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
  2. NM_001243163.1NP_001230092.1  transcription factor SOX-5 isoform c

    See identical proteins and their annotated locations for NP_001230092.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5_ coding region and lacks an in-frame exon in the 3_ coding region, compared to variant 1. This results in a shorter protein (isoform c), compared to isoform a.
    Source sequence(s)
    AC161059, AC167021, AK081802, BC110478
    Consensus CDS
    CCDS57469.1
    UniProtKB/TrEMBL
    B2KFM4, X2FV61
    Related
    ENSMUSP00000107378.2, ENSMUST00000111749.8
    Conserved Domains (1) summary
    cd01388
    Location:471542
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
  3. NM_001347506.1NP_001334435.1  transcription factor SOX-5 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in a protein (isoform d) with a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AC167021, AK160154
    Consensus CDS
    CCDS85183.1
    UniProtKB/TrEMBL
    Q3TVF9
    Related
    ENSMUSP00000107377.2, ENSMUST00000111748.8
  4. NM_011444.3NP_035574.2  transcription factor SOX-5 isoform a

    See identical proteins and their annotated locations for NP_035574.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC161059, AC167021, AK081802, BC110478
    Consensus CDS
    CCDS39702.1
    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    UniProtKB/TrEMBL
    B2KFM9
    Related
    ENSMUSP00000047567.8, ENSMUST00000038815.14
    Conserved Domains (1) summary
    cd01388
    Location:555626
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    143774151..144728008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165995.1XP_036021888.1  transcription factor SOX-5 isoform X16

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:493564
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  2. XM_011241579.3XP_011239881.1  transcription factor SOX-5 isoform X6

    See identical proteins and their annotated locations for XP_011239881.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:543614
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  3. XM_011241582.3XP_011239884.1  transcription factor SOX-5 isoform X16

    See identical proteins and their annotated locations for XP_011239884.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:493564
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  4. XM_011241577.3XP_011239879.1  transcription factor SOX-5 isoform X6

    See identical proteins and their annotated locations for XP_011239879.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:543614
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  5. XM_036165997.1XP_036021890.1  transcription factor SOX-5 isoform X18

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:458529
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  6. XM_036165992.1XP_036021885.1  transcription factor SOX-5 isoform X13

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:507578
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  7. XM_036165986.1XP_036021879.1  transcription factor SOX-5 isoform X12

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:508579
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  8. XM_036165988.1XP_036021881.1  transcription factor SOX-5 isoform X12

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:508579
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  9. XM_036165996.1XP_036021889.1  transcription factor SOX-5 isoform X18

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:458529
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  10. XM_036165991.1XP_036021884.1  transcription factor SOX-5 isoform X13

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:507578
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  11. XM_011241581.3XP_011239883.1  transcription factor SOX-5 isoform X12

    See identical proteins and their annotated locations for XP_011239883.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:508579
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  12. XM_036165993.1XP_036021886.1  transcription factor SOX-5 isoform X13

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:507578
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  13. XM_036165987.1XP_036021880.1  transcription factor SOX-5 isoform X12

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:508579
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  14. XM_011241578.3XP_011239880.1  transcription factor SOX-5 isoform X6

    See identical proteins and their annotated locations for XP_011239880.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:543614
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  15. XM_006506938.5XP_006507001.1  transcription factor SOX-5 isoform X8

    See identical proteins and their annotated locations for XP_006507001.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:535606
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  16. XM_030255287.2XP_030111147.1  transcription factor SOX-5 isoform X9

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:534605
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  17. XM_006506931.5XP_006506994.1  transcription factor SOX-5 isoform X1

    See identical proteins and their annotated locations for XP_006506994.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:584655
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  18. XM_006506932.5XP_006506995.1  transcription factor SOX-5 isoform X2

    See identical proteins and their annotated locations for XP_006506995.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:583654
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  19. XM_006506942.5XP_006507005.1  transcription factor SOX-5 isoform X15

    See identical proteins and their annotated locations for XP_006507005.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:499570
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  20. XM_006506934.5XP_006506997.1  transcription factor SOX-5 isoform X4

    See identical proteins and their annotated locations for XP_006506997.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:549620
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  21. XM_006506935.5XP_006506998.1  transcription factor SOX-5 isoform X5

    See identical proteins and their annotated locations for XP_006506998.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:548619
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  22. XM_017321475.3XP_017176964.1  transcription factor SOX-5 isoform X17

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:472543
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  23. XM_030255290.2XP_030111150.1  transcription factor SOX-5 isoform X14

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    UniProtKB/TrEMBL
    E9PVR0
    Related
    ENSMUSP00000133041.3, ENSMUST00000170367.9
    Conserved Domains (1) summary
    cd01388
    Location:506577
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  24. XM_006506933.5XP_006506996.1  transcription factor SOX-5 isoform X3

    See identical proteins and their annotated locations for XP_006506996.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:556627
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  25. XM_006506939.5XP_006507002.1  transcription factor SOX-5 isoform X10

    See identical proteins and their annotated locations for XP_006507002.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:521592
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  26. XM_011241580.4XP_011239882.1  transcription factor SOX-5 isoform X11

    See identical proteins and their annotated locations for XP_011239882.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:520591
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  27. XM_036165998.1XP_036021891.1  transcription factor SOX-5 isoform X18

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:458529
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  28. XM_030255289.2XP_030111149.1  transcription factor SOX-5 isoform X13

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:507578
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  29. XM_006506940.5XP_006507003.1  transcription factor SOX-5 isoform X12

    See identical proteins and their annotated locations for XP_006507003.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:508579
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  30. XM_006506936.5XP_006506999.1  transcription factor SOX-5 isoform X6

    See identical proteins and their annotated locations for XP_006506999.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:543614
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  31. XM_006506941.5XP_006507004.1  transcription factor SOX-5 isoform X13

    See identical proteins and their annotated locations for XP_006507004.1

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:507578
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  32. XM_036165989.1XP_036021882.1  transcription factor SOX-5 isoform X12

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:508579
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  33. XM_006506937.5XP_006507000.1  transcription factor SOX-5 isoform X6

    See identical proteins and their annotated locations for XP_006507000.1

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:543614
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  34. XM_036165999.1XP_036021892.1  transcription factor SOX-5 isoform X18

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:458529
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  35. XM_036165985.1XP_036021878.1  transcription factor SOX-5 isoform X7

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:542613
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  36. XM_036165984.1XP_036021877.1  transcription factor SOX-5 isoform X6

    UniProtKB/Swiss-Prot
    O88184, O89018, P35710
    Conserved Domains (1) summary
    cd01388
    Location:543614
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  37. XM_036165990.1XP_036021883.1  transcription factor SOX-5 isoform X12

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:508579
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  38. XM_036165994.1XP_036021887.1  transcription factor SOX-5 isoform X13

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:507578
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  39. XM_036166000.1XP_036021893.1  transcription factor SOX-5 isoform X18

    UniProtKB/TrEMBL
    X2FV61
    Conserved Domains (1) summary
    cd01388
    Location:458529
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  40. XM_006506945.5XP_006507008.1  transcription factor SOX-5 isoform X20

    See identical proteins and their annotated locations for XP_006507008.1

    Conserved Domains (1) summary
    cd01388
    Location:233304
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
  41. XM_036166001.1XP_036021894.1  transcription factor SOX-5 isoform X19

    Conserved Domains (1) summary
    cd01388
    Location:262333
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...