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Rps14 ribosomal protein S14 [ Mus musculus (house mouse) ]

Gene ID: 20044, updated on 8-Dec-2022

Summary

Official Symbol
Rps14provided by MGI
Official Full Name
ribosomal protein S14provided by MGI
Primary source
MGI:MGI:98107
See related
Ensembl:ENSMUSG00000024608 AllianceGenome:MGI:98107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2600014J02Rik
Summary
Predicted to enable mRNA 5'-UTR binding activity; small ribosomal subunit rRNA binding activity; and translation regulator activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including erythrocyte differentiation; negative regulation of transcription by RNA polymerase II; and ribosomal small subunit biogenesis. Located in mitochondrion. Is expressed in early conceptus and metanephros. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Orthologous to human RPS14 (ribosomal protein S14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 739.0), liver E14 (RPKM 644.6) and 28 other tissues See more
Orthologs
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Genomic context

See Rps14 in Genome Data Viewer
Location:
18 E1; 18 34.4 cM
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (60907668..60911618)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (60774596..60778546)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA G630071F17 gene Neighboring gene VISTA enhancer mm1623 Neighboring gene N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 Neighboring gene 40S ribosomal protein S16 pseudogene Neighboring gene microRNA 5107 Neighboring gene CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC86125

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA 5'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA 5'-UTR binding ISO
Inferred from Sequence Orthology
more info
 
enables small ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
enables translation regulator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosomal small subunit assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in translation ISO
Inferred from Sequence Orthology
more info
 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse NAS
Non-traceable Author Statement
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020600.4NP_065625.2  40S ribosomal protein S14

    See identical proteins and their annotated locations for NP_065625.2

    Status: VALIDATED

    Source sequence(s)
    AK028106, AV490910, BY149058
    Consensus CDS
    CCDS29274.1
    UniProtKB/Swiss-Prot
    P62264, Q544W4
    UniProtKB/TrEMBL
    A0A6P5P1U5, A0A8C6MPG7
    Related
    ENSMUSP00000025511.4, ENSMUST00000025511.11
    Conserved Domains (1) summary
    PTZ00129
    Location:1140
    PTZ00129; 40S ribosomal protein S14; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    60907668..60911618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)